Institute for Integrative Biology of the Cell
April 12th, 2024 by B3S Dept
Epigenetics: combining flexible and rigid regions into a single structure to ensure genome replication and stability
The AMIG team at I2BC, in collaboration with teams from the Institut Curie and the Synchrotron Soleil, shows that the CAF-1 protein combines in its spatial organization flexible regions and rigid modules to deposit histones on DNA and effectively couple this process to DNA synthesis.
April 12th, 2024 by B3S Dept
A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity
April 12th, 2024 by BioCell Dept
A Fatty Acid Anabolic Pathway in Specialized-Cells Sustains a Remote Signal that Controls Egg Activation in Drosophila
While egg activation, i.e. oocyte to embryo transition, was not known to depend on physiological non-genital signal, this study shows that in Drosophila it depends on a very-long-chain-fatty-acid produced in the oenocytes (lipid metabolism specialized cells).
April 12th, 2024 by Genome Biology Dept
Transcription-induced DNA supercoiling clears RNA polymerase’s path in bacterial chromatin
Positive DNA supercoiling generated ahead of RNA polymerase during transcription elongation dislodges nucleoid-structuring protein H-NS from the DNA.
April 12th, 2024 by Genome Biology Dept
Uncoupling programmed DNA cleavage and repair
scrambles the Paramecium somatic genome
scrambles the Paramecium somatic genome
No Ku – no cut: how the ciliate Paramecium tetraurelia protects its somatic genome from translocations and aberrant chromosome fragmentation during developmentally programmed rearrangements.
takes part in
