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Département Virologie

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  • Lundi 2 octobre 11:00-12:00 - Dr Arnaud Morris - Centre d'Immunologie et des Maladies Infectieuses, La Pitié Salpêtrière, Paris

    Learning from viruses to dissect the cell biology of antigen presentation

    Résumé : The work of our team is at the interface between cellular biology, virology and immunology. We characterize the interactions between viruses and immune cells with a focus on viral antigen presentation by infected cells to T lymphocytes. Our aim is to identify novel sources of viral antigens and to define unconventional cellular pathways involved in antigen processing that influence the activation of T lymphocytes. During this presentation, I will highlight the diversity of antigens that are encoded by virally infected cells, in particular the usage of alternative reading frames as a source of antigenic peptides. I will also present on going work on protein-adaptor, involved in autophagy, and their role in antigen degradation and T cell activation.

    Lieu : Salle de séminaires - Bâtiment 14, campus de gif

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