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Accueil > Départements > Biologie des Génomes > Carmela GIGLIONE : Maturation des protéines, destinée cellulaire et thérapeutique

In vivo N-terminal maturation of proteins synthesized in plant mitochondria

This data should be quoted as part of the review paper by Giglione & Meinnel (2001) Trends Plant Sci. 6(12), 566-572

If some data or information is missing or erroneous, please feel free to email your corrections to Thierry Meinnel so that this table can be up-dated immediately.

Gene name
a

Protein name and
functiona

Organism

b

N-terminal cleavages

c

Refs

d

Proteins retaining the
N-formyl

 ???

Uncharacterized 32 kDa
protein

Bb

f-Met-Ile

1

(i) Proteins undergoing N-formyl
cleavage only

atp1

ATP synthase sub-unit 1

At, Bb

f>Met-Glu

2,3

atp9

ATP synthase sub-unit 9

At

f>Met-Leu

4

nad9

NADH dehydrogenase sub-unit
9

Po

f>Met-Asp

5

(ii) Proteins undergoing N-formyl
cleavage and N-methionine cleavage

cob

Apocytochrome B

Po

fMet>Thr

6

nad7

NADH dehydrogenase sub-unit
7

Bb, Po

fMet>Thr

2,5,7

rps10

Ribosomal protein S10

Bb

fMet>Val

1

rps12

Ribosomal protein S12

p align="CENTER">Bb

fMet>Pro

1

(iv) Proteins undergoing extensive
cleavages

atp6

ATP synthase sub-unit 6

Bb

delta(fMet1-Pro30)>Ser

8

coxII

cytochrome c oxidase subunit
2

At

delta(fMet1-Cys14)>Asp

4


a Genes encoding several proteins of the mitochondrion from higher plants are reported.
b At, Arabidopsis thaliana ; Bb, broad bean (Vicia faba) ; Po, potato (Solanum tuberosum).
c N-terminal sequence of the corresponding proteins is indicated. The final deduced cleavage site is indicated by >, representing cleavage by PDF (f>Met) or by PDF plus MAP (fMet>) or by further peptidases if the extent of the cleavage is larger (deltais the corresponding deletion). f is N-formyl.
d references

1. Maffey, et al. (1997) Mol. Gen. Genet. 254, 365-71.
2. Leterme & Boutry. (1993) Plant Physiol. 102, 435-43.
3. Kruft, et al. (2001) Plant Physiol. 127, 1694-710.
4. Jansch, et al. (1996) Plant J. 9, 357-68.
5. Herz, et al. (1994) J. Biol. Chem. 269, 2263-9.
6. Braun & Schmitz. (1993) FEBS Lett. 316, 128-32.
7. Gabler, et al. (1994) Mol. Gen. Genet. 244, 33-40.
8. Macfarlane, et al. (1990) Curr. Genet. 18, 87-91.

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