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Accueil > Départements > Biochimie, Biophysique et Biologie Structurale > Benoit GIGANT & Julie MENETREY : Biochimie Structurale des Microtubules, des Kinésines et de leurs Cargos

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October 16th, 2017 
 :

Our latest paper on Structural plasticity of the N-terminal capping helix of the TPR domain of kinesin light chain by The Quyen Nguyen et al. is now online on the PLOS One website.

October 16th, 2017 
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The Quyen Nguyen defended his PhD thesis "Structural characterization of JIP1 recruitment by kinesin1 light chain (KLC)" . Congratulations Dr Nguyen !

November 13th-16th, 2017
 : save the date !

Mélanie, Fernando and Valérie organized a CNRS Formation Entreprise workshop dedicated to protein purification. This is a 3,5 days hands-on course centered around parallel practicals in small groups. Register here !
 
 
 
 
 
 
 
 
 
 
 

September 24th, 2017

Pour la 3e année consécutive, notre équipe a participé à la Course Enfants sans Cancer qui a eu lieu au Domaine National de Saint-Cloud, afin de collecter des fonds pour soutenir la recherche sur les cancers de l’enfant.
1 enfant sur 440 est atteint du cancer avant 15 ans. Tous les ans, en France 2500 enfants et adolescents sont diagnostiqués et 500 en meurent.
Julie, Paloma, Valérie, Isabel et Fernando remercient tous les généreux donateurs qui leur ont permis de participer à cette course ! Les enfants malades et la recherche vous remercient ! Comme chaque année, tous les fonds collectés serviront à financer un nouveau traitement innovant contre les cancers des enfants.

As in 2015 and 2016, our team supports Imagine for Margo – Children without Cancer. This year, we were glad to attend the 6th edition of the Children without Cancer race that took place Sunday September 24 in Domaine National of Saint Cloud near Paris.
The goal of this race is to collect fundings for specific research programs that focus on finding innovative and more effective treatments against pediatric cancers.
Many thanks !
GO, FIGHT, WIN !
 

July 11th, 2017

We are pleased to introduce the Cytoskeleton Club : first meeting will take place on Tuesday September 12 at the bd 34 library. Christophe Le Clainche will talk about “Understanding cellular force response through the in vitro reconstitution of mechanosensitive protein machineries”.
Save the dates for the next meetings : 10-oct-2017, 14-nov-2017, 12-dec-2017, 9-jan-2018, 13-feb-2018, 13-mar-2018, 10-apr-2018, 8-may-2018, 12-june-2018 and 10-july-2018. More infos here.

July 10th, 2017


Our latest paper on the structure of Kif2C bound to tubulin by Weiyi Wang et al. is now online on the Nature Communications website.

July 5th, 2017


We were glad to welcome chinese students from Huazhong University of Science and Technology for a sneak peek of our research topics.
 
 
 
 
 
 
 
 

July 3rd-4th, 2017


We were at the 3rd French Microtubule Network meeting in Versailles. Julie, Fernando and Valérie presented a poster, Benoît gave a talk. Thank you to the organizing committee for this very successful meeting !

June 19th, 2017


Fernando passed his mid-thesis evaluation with Olena Pylypenko (Curie Institute, Paris) as committee member.
 
 
 
 
 
 
 
 

June 12th, 2017


Andrew CARTER (MRC, Cambridge) gave a talk on “Transporting cargo over long distances : insight from dynein/dynactin structures”.

 

 

 

 

 

 

June 6th, 2017


The paper "Mechanism of microtubule stabilization by taccalonolide AJ" by Wang Y. et al. is now online on the Nature Communications website.

May 15th-18th, 2017


Mélanie and Valérie organized a CNRS Formation Entreprise workshop dedicated to protein purification. This is a 3,5 days hands-on course centered around parallel practicals in small groups. Next workshop in November ! Register here !

 

 

 

 

 

 

 

 

 

May 8th-12th, 2017


Benoît was at the Jacques-Monod conference in Roscoff (Brittany) on actin and microtubule cytoskeleton.

April, 2017


A day in the life of our lab : Sharing good times...

April, 2017


Welcome to Elizabeth CESARD (left) and Yacine DJABALI (right) from Paris-Sud University, who recently joined our team for their internship. Elizabeth is a Master 1 student in Healthcare Biology (Plateforme : Transdisciplinaire pour la Biochimie et les Biotechnologies). Yacine is a L2 student in Biology-Chemistry. Elizabeth and Yacine are going to work on kinesin and tubulin projects under the supervision of Fernando Vilela/Julie Ménétrey and Valérie Campanacci, respectively.

 

 

 

 

March 22nd-24th, 2017


Paloma FERNANDEZ VARELA attended the ARBRE-MOBIEU fifth meeting and first COST-sponsored plenary meeting. She presented preliminary results by switchSENSE, an innovate technology available in our institute.

February 14th, 2017


Our paper "The structural switch of nucleotide-free kinesin" by Cao L. et al. is now online on the Nature Scientific Reports website.

February, 2017


A day in the life of our lab :
Multi-(flask)-mutator thesis…..

 

 

 

 

 

 

 

 

 

 

 

January 19th-20th, 2017


Valérie and Benoît were at the 12th SOLEIL Users’ Meeting - SUM17 in Palaiseau.

 

 

 

 

 

 

 

 

January 16th, 2017


We are glad to welcome Hajar AIT BELLA (left) and Christèle GOBILLON (right), who have joined our team since Monday, 2nd January. Hajar is a student of Master 2 in BioSciences and Healthcare Engineering (Molecular Biotechnologies and Bio engineering, Pathophysiology, Therapeutics) from Faculty of Sciences and Technologies in Nancy. Christèle is a BTS student from Lycée de la Vallée de Chevreuse in Gif-sur-Yvette. Hajar and Christèle are going to work on tubulin projects under the supervision of Benoît Gigant/Valérie Campanacci and Soraya Cantos Fernandes, respectively.

FOLLOW US - 2016

December 25th, 2016


Season’s greetings from MiKiCa !

December 13th-16th, 2016


We were at the GTBio conference in Obernai. Benoît gave a talk on the the structure of a tubulin-kinesin complex. Quyen and Valérie presented a poster on their work.

November, 2016


A day in the life of our lab : Protein preparation for nanoDSF experiments (coll. Catherine BIRCK, IGBMC, Illkirch) granted by FRISBI.

 

 

 

 

 

 

 

October, 2016


A day in the life of our lab :
Multi-(task)-processor thesis…..

 

 

 

 

 

 

October 5th-7th, 2016


We were at the 1st I2BC Science Days. Benoît gave a talk on kinesin’s motility. Quyen and Fernando presented a poster on their thesis work.

 

 

 

 

 

 

 

 

 

September 27th, 2016


Congratulations to LuYan CAO who successfully defended her PhD thesis entitled “Structural Basis of Kinesin’s Motility”. Welcome Dr Cao !

September 25th, 2016


As in 2015, our team supports “Imagine for Margo – Children without Cancer”. This year, we were glad to be amongst 3’800 runners and walkers for the 5th edition of the “Children without Cancer” race that took place in Domaine National of Saint Cloud near Paris.
Many thanks to all our donors who allowed us to collect 845 €.
Contributions are still welcome here.
See you next year ! GO, FIGHT, WIN !

September 6th, 2016


Coralie CARIVENC defended her M2Pro "Structural Biochemistry and Proteomics Metabolomics".

 

 

 

 

 

 

 

 

 

 

August 30th, 2016


We are on Twitter ! Feel free to become one of our followers :

August, 2016


We are glad to present our team logo designed by Weiyi Wang :

July, 2016


A day in the life of our lab : Cleaning day...and payback time.

July 4th-7th, 2016


Quyen NGUYEN and Marcel KNOSSOW were at the AFC 2016 (Association Française de Cristallographie) congress held in Marseille. Quyen presented his poster entitled « Interaction between Kinesin1 and its JIP1 adaptor protein », and Marcel co-organized the session 8 "Dynamique des complexes Macromoléculaires”.

 

 

 

 

 

 

 

June 14th, 2016


Luyan Cao receiving her award from Zhai Jun, Ambassador of the People’s Republic of China to France

Congratulations to LuYan CAO who has been granted « the 2015 National Award for Outstanding Self-financed Chinese Students Study Abroad » by China Scholarship council.

 

 

 

 

 

 

 

June, 2016


A day in the life of our lab : Exploring 3D protein structure.

 

 

 

 

 

 

 

 

 

May 29th-June 1st, 2016


Benoît GIGANT attended the 2016 EMBL symposium entitled « Microtubules : From Atoms to Complex Systems », held in Heidelberg, Germany.

 

 

 

 

 

 

May 20th-27th, 2016


La Vieille Perrotine - 2016
La Vieille Perrotine - 2016

Fernando VILELA attended the 3rd RéNaFoBIS National School – Oléron 2016 in Ile d’Oléron, France.

 

 

 

 

 

 

 

 

May 23rd, 2016


Mélanie Rambaud and Maëlle Leclerc
Mélanie Rambaud and Maëlle Leclerc

Welcome to Mélanie RAMBAUD (right) and Maëlle LECLERC (left), BTS students, who have joined our team this Monday for their 7 weeks internship. Mélanie and Maëlle are going to work on tubulin/kinesin related projects under the supervision of Valérie Campanacci and Soraya Cantos Fernandes, respectively.

 

May, 2016


A day in the life of our lab : Regenerating columns.

April 11th, 2016


Pierre Martini
Pierre Martini

Pierre MARTINI, student of L2 « Sciences de la vie mention Biologie » at Paris Sud University in Orsay has joined our team on April 11th. During his six weeks traineeship he will learn about laboratory work under the supervision of Mélanie Chenon.

 

 

 

 

 

April, 2016


A day in the life of our lab : Studying protein-protein interaction by surface plasmon resonance (SPR) (Weiyi, left) and protein shape by small-angle x-ray scattering (SAXS) on SWING beamline (Paola, right).

March 21st-25th, 2016

Atelier de BioCristallographie 2016 / 2016 BioCrystallography Workshop.

Atelier de BioCristallographie 2016

This workshop aims to introduce participants to structure determination of biological macromolecules by X-ray crystallography. For more information, please visit the workshop website here.

March, 2016


A day in the life of our lab : celebration for MiKiCa’s 1st anniversary !

February, 2016


A day in the life of our lab : crystals fishing and freezing before synchrotron beamtime.

February 22nd, 2016


Our paper "Structure of a truncated form of the Leucine Zipper II of JIP3 reveals an unexpected anti-parallel coiled-coil arrangement" by Llinas P. et al. is now online on the Acta Crystallographica section F website (March 2016 issue).

 

February 1st, 2016


Coralie Carivenc
Coralie Carivenc

Coralie CARIVENC, student of M2Pro "Structural Biochemistry and Proteomics Metabolomics" at Paul Sabatier University in Toulouse joins our team on February 1st for her 6 months master internship. She works in one of the kinesin-1/cargo project supervised by Paloma Fernández-Varela and Julie Ménétrey.

 

 

February 1st-4th, 2016


Paloma FERNANDEZ-VARELA attended the VII International Conference of the Institute for Biocomputation and Physics of Complex Systems (BIFI). This conference was followed by the 4th ARBRE meeting. Both meetings were held in Zaragoza, Spain.

January, 2016


A day in the life of our lab : Fernando preparing protein-protein complex samples for high throughput crystallization trials.

 

 

 

 

 

 

 

 

 

 

 

 

 

January 10th - 14th, 2016

Luyan CAO attended the 23rd Jerusalem School in Life Sciences – Computational and Structural Biology. The conference took place at the Israel Institute for Advanced Studies located at The Hebrew University in Jerusalem, Israel.

Jerusalem, the Old City - photo by Lu Yan Cao
Jerusalem, the Old City - photo by Lu Yan Cao

 

FOLLOW US - 2015

December, 2015

A day in the life of our lab : Soraya purifying proteins with one of our chromatography system.

November, 2015

A day in the life of our lab : our team collecting data on Proxima-1 beamline at the SOLEIL synchrotron.

September 27th, 2015

Our team supports “Imagine for Margo – Children without Cancer”, association created in 2011 to raise funds for research on childhood cancers. Yan, Quyen, Julie and Valérie joined 2’500 runners and walkers for the 4th edition of the “Children without Cancer” race that took place last Sunday in Domaine National of Saint Cloud near Paris.
Many thanks to all our donors who allowed us to collect 755 € ! You can still contribute here. Funds will finance the therapeutic eSMART trials of the ITCC network (Innovative Therapies for Children with Cancer).
See you next year ! GO, FIGHT, WIN !

Our team, a few minutes before running : Julie Ménétrey, The Quyen Nguyen, Valérie Campanacci, Lu Yan Cao (from left to right).

September 13th - 15th, 2015

Benoît GIGANT was invited to give a talk at the 53rd Annual Meeting of the Biophysical Society of Japan held in Kanazawa, Japan. He presented his work during the "Conformational switching of tubulin and its physiological function" symposium.

The 53rd Annual Meeting of the Biophysical Society of Japan

July 6th and 7th, 2015

We were to the 2nd French Microtubule Network Meeting in Grenoble. The aim of this conference is to bring together French microtubule specialists and to favor scientific exchange and collaborations, through informal discussions.

Grenoble seen from the Bastille fortress, photo by Lu Yan Cao

June 25th, 2015

Fernando Vilela

Congratulations to Fernando VILELA, Master student under the supervision of Julie Ménétrey, who obtained a PhD funding from Université Paris-Saclay (starting October 2015).

Fernando graduated from Porto University, Portugal, and joined the lab in October 2014 thanks to an Erasmus scholarship.

 

 

June 16th and 17th, 2015

Congratulations to Lu Yan CAO who won the prize for the best oral presentation at the Journées de l’Ecole Doctorale 2015.

Luyan Cao

Yan graduated in Biotechnology at Tongji University, China, and is currently a PhD student under the supervision of Marcel Knossow and Benoît Gigant.

June 15th and 16th, 2015

We organized the« Nanotemper Technologies Workshop : Interactions and beyond » in collaboration with Nanotemper and ARBRE. This workshop, combining theoretical and practical sessions, aimed to introduce powerful technologies to study interactions between biological molecules and protein folding/stability.

Nanotemper Technologies Workshop : Interactions and beyond {PNG}

Please visit the I2BC facility website (link)

June 1st, 2015

We are very pleased to announce the merging of the Ménétrey and Gigant groups.

Team “Structural Biochemistry of Microtubules, Kinesins and their Cargos”

 


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