Résumé : The asymmetric cell division cycle of the non-pathogenic Gram-negative bacterium Caulobacter crescentus provides a simple and genetically tractable system to dissect transcriptional regulatory cascades controlling cell cycle events. Additionally, as Caulobacter cells remodel their cell poles at defined times during the cell cycle, the implementation of cell polarity and its functional consequences can be conveniently studied. We have identified polarity factors in Caulobacter and are exploring how these factors act coordinately to control polar morphogenesis, and we are now exploring if they function similarly in related obligate intracellular pathogens.
Invitée par Yoshiharu YAMAICHI, Equipe Intégrité du génome et de la polarité cellulaire chez la bactérie
Lieu : Salle de séminaires - Bâtiment 26, campus de Gif