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2 octobre 2017: 1 événement

  • Département Virologie

    Lundi 2 octobre 11:00-12:00 - Dr Arnaud Morris - Centre d'Immunologie et des Maladies Infectieuses, La Pitié Salpêtrière, Paris

    Learning from viruses to dissect the cell biology of antigen presentation

    Résumé : The work of our team is at the interface between cellular biology, virology and immunology. We characterize the interactions between viruses and immune cells with a focus on viral antigen presentation by infected cells to T lymphocytes. Our aim is to identify novel sources of viral antigens and to define unconventional cellular pathways involved in antigen processing that influence the activation of T lymphocytes. During this presentation, I will highlight the diversity of antigens that are encoded by virally infected cells, in particular the usage of alternative reading frames as a source of antigenic peptides. I will also present on going work on protein-adaptor, involved in autophagy, and their role in antigen degradation and T cell activation.

    Lieu : Salle de séminaires - Bâtiment 14, campus de gif

    En savoir plus : Département Virologie

2 octobre 2017: 1 événement

  • Département Biochimie, Biophysique et Biologie Structurale

    Lundi 2 octobre 14:00-17:00 - Pierre Chervy - I2BC equipe Interactions et mécanismes d’assemblage des protéines et des peptides

    caractérisation biophysique des interactions entre le Lanréotide et des membranes lipidiques

    Lieu : amphithéâtre J. TALAIRACH - Neurospin, CEA Saclay

    En savoir plus : Département Biochimie, Biophysique et Biologie Structurale

2 octobre 2017: 1 événement

  • Evenements 3D_CHROME

    Du 2 octobre 13:00 au 3 octobre 18:00 -

    3D-CHROME Workshop : “Modelling of 3D genome organisation”

    Résumé : MGO2017 Workshop - “Modelling of 3D Genome Organization - Integrating genomics and microscopy data”
    Chromosomes need to be precisely organized within the limited nuclear volume that is available in interphase. Genomics and microscopy studies have revealed that 3D genome organization directly mirrorsbiological functions like gene regulation, recombination and DNA replication and repair. Biophysical and mathematical modelling can provide further insights whether 3D genome organization dictates functional outputs and how much variation is present between individual cells and over time.
    During the workshop 8 internationally renowned experts will discuss recent projects where genomics and microscopy studies are integrated using biophysical and modelling approaches.
    Confirmed speakers :
    • Kerstin Bystricky - LBME, Toulouse
    • Luca Giorgetti, FMI, Switzerland
    • Ivan Junier, TIMC-IMAG, Grenoble
    • Jop Kind, Hubrecht Institute, The Netherlands
    • Julien Mozziconacci, UPMC, Paris
    • Mario Nicodemi, University of Naples and INFN, Italy
    • Cédric Vaillant, Ecole Normale Supérieure, Lyon
    • Juan Vaquerizas, MPI for Molecular Biomedicine, Germany
    The workshop is aimed at scientists with backgrounds in (bio)physics, biology and bioinformatics (PhD students, postdocs, engineers, young and senior scientists). Registration is free of charge but mandatory ( number of participants is strictly limited to 150 participants, on a first-come basis, with deadline on the 24th of July. We therefore advise to register as soon as possible. The workshop is organized by the University Paris-Saclay 3D-CHROME Initiative with support from LABEX PALM and LABEX SPS.
    The workshop will be followed by a half-day bioinformatics tutorial on Hi-C data analysis (afternoon of October 3rd) where tools for Hi-C data processing and the calling of functional domains will be discussed by Nicolas Servant (Insitut Curie) and Kai Kruse (MPI for Molecular Biomedicine, Germany). Registration to this tutorial is limited to 20 participants, with selection based on motivation. The tutorial is organized by the University Paris-Saclay PSay-CompBioInitiative.
    Further information at and in the flyer.

    Lieu : Auditorium - Bâtiment 21, campus de gif

    En savoir plus : Evenements 3D_CHROME