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One-year Postdoctoral position
A one-year postdoctoral position funded by DIM1 Health (Région Ile-de France) starting beginning of 2021 is available in the research group "Transcription regulation in the malaria parasite" to work on characterization of a nuclear protein complex from Plasmodium falciparum.
The postdoctoral researcher will work in a project combining parasitology, proteomics and biochemistry, as part of a new ATIP-Avenir team at the Genome Biology department of the I2BC. The goal of the project is to determine how two essential nuclear proteins from the malaria parasite, Plasmodium falciparum, interact to then design protein complex inhibitors. The postdoc will collaborate with two teams, one from the I2BC and one from IPSIT, to reach the project goals.

The I2BC is a University of Paris-Saclay/CNRS/CEA research unit situated in the research campus of Gif-sur-Yvette, 35km southwest of Paris. The campus is in close proximity to a natural park and is deserved by public transportation with direct access to Paris. The institute hosts around 750 people among 60 research teams and 14 state-of-the-art technical facilities.

To apply, please send a letter of motivation, CV and the coordinates of 2 referees to Joana Santos.

Two-years Postdoctoral position

A two-year postdoctoral position funded by the French National Research Agency (ANR) is available at the research group of « Intracellular Trafficking and Organelle Biogenesis of Toxoplasma » in the Institute for Integrative Biology of the Cell (I2BC), UMR 9198 CNRS-CEA, and Paris-Saclay University (South Paris University). Our group is interested in the intracellular trafficking of proteins and lipids that are involved in the biogenesis of secretory organelles known to play key roles in infection of hosts by Toxoplasma gondii. The current project will focus on the functional analyses of newly identified parasite’s proteins that bind to lipids, which are likely involved in the membrane trafficking from the post-Golgi/endosome-like compartement (ELC) to the secretory organelles of T. gondii. By using a combination of approaches including cell biology and biochemistry, we aim to decipher the roles of these novel proteins in the formation of membrane-bound vesicles that are required for secretory organelle biogenesis.

The applicant should have a strong background in cell and molecular biology. Prior experience in imaging (confocal microscopy) analyses and biochemical methods to study protein-protein (IP) will be highly advantageous. The ideal candidate should be highly motivated, curious and will be actively involved in interdisciplinary research with renowned laboratories and core facilities of the Institute for Integrative Biology of the Cell (I2BC). A good level in English (written and spoken) is required. Review of applications will begin immediately until the position filled.

Interested candidates should send by e-mail their CV, a list of two or three references and a cover letter stating their research experience and interests to Dr Stanislas Tomavo

There are no other open position in the Institute at the moment.

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