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2 septembre 2019: 1 événement

  • Département Biologie des Génomes

    Lundi 2 septembre 11:00-12:00 - Chloé GIRARD - Stanford University, USA

    Recombining genomes : when, where and how much ?

    Résumé : Meiotic recombination is a major driving force of evolution : not only can it create new and advantageous genetic combinations, but it can also break down existing ones. The frequency and distribution of crossovers dictate which traits are inherited together and which ones are re-assorted to produce new combinations on which selection can act. Crossover distribution is neither uniform nor random, but the mechanisms and evolutionary forces that impose crossover patterning are poorly understood. Understanding when, where, and how much genomes recombine is of major importance to apprehend causes of infertility and to reveal the forces contributing to genome evolution. Chloe Girard has been studying the mechanisms that regulate meiotic recombination in both the plant Arabidopsis and the nematode C. elegans, and will share insights about factors that limit crossover formation in wild type. She will also present future directions for her research about how crossover distribution and frequency can be influenced by polymorphism density and external stress conditions.

    Lieu : Salle A. Kalogeropoulos - bâtiment 400 - campus d'Orsay

    En savoir plus : Département Biologie des Génomes