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2 avril 2021: 1 événement

  • Département Biologie des Génomes

    Vendredi 2 avril 16:00-17:00 - Sebastian Lourido

    Defining transitions in a parasitic life cycle [note : CHANGE OF TIME]

    Résumé : For over half a billion years, members of the phylum Apicomplexa have existed as parasites and symbionts of all major animals on earth. The group includes major human pathogens like the etiological agents of malaria and toxoplasmosis. Our lab employs unbiased approaches in functional genomics and proteomics to delve into the major transitions of the apicomplexan life cycle and understand their molecular underpinnings. Here, I will discuss the implementation of genome-scale CRISPR-based screens to identify new components of the machinery for host cell invasion, and describe our recent discovery of the master regulator of chronic differentiation in Toxoplasma gondii. These vignettes will illustrate the possibilities brought about by new technologies to understand cell biology of apicomplexans. We hope such studies will provide insight into microbial pathogenesis and a reference point for the vast diversity of the eukaryotic radiation.
    Contact : Joana SANTOS <joana.santos>

    En savoir plus : Département Biologie des Génomes