Institute for Integrative Biology of the Cell

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D'AUTREAUX B3S

january 13th, 2026 by B3S Dept

Cross-regulation of iron-sulfur cluster biosynthesis by frataxin and ferredoxin-2

Tight regulation of Fe-S clusters biosynthesis via a mutually antagonistic binding of frataxin and ferredoxin-2 to the assembly machinery, with several important implications for the Friedreich’s ataxia disease caused by frataxin deficiency

Nature

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