Institute for Integrative Biology of the Cell

Khul Biocell

May 10th, 2022 by Cell Biology Dept

Starting the engine of the powerhouse: mitochondrial transcription and beyond
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Mitochondria are the powerhouses of cells thanks to the oxidative phosphorylation system partially encoded by a small mitochondrial genome (mtDNA). Miranda et al review our current knowledge on mtDNA expression, associated disease phenotypes, and how mtDNA and nuclear gene expression are coordinated.

GIGANT - B3S

April 15th, 2022 by B3S Dept

Structural convergence between inhibitors and a regulator of microtubule dynamics
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A region of CPAP, a protein regulating the length of the centrioles, is found to have a tubulin binding mode similar to that of bacterial and fungal peptide-like metabolites which inhibit cell division.

Esclatine Glon

april 15, 2022 by Virology Dept

Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein
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BHRF1, a multifunctional viral protein expressed during Epstein-Barr virus reactivation, modulates mitochondrial dynamics and induces MT hyperacetylation to escape innate immunity. Moreover, the loss of MT hyperacetylation impedes BHRF1 to initiate mitophagy, which is essential to inhibit the signaling pathway.

Quaranta b3S

march 18th, 2022 by B3S Dept

Insights into the photocatalytic cycle highlighted at I2BC
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An iron–porphyrin bearing urea groups exhibits exceptional high performance for CO2-to-CO photocatalytic reduction.

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Calendar

I2BC scientific Axis 1 seminar

 Auditorium Building 21, Gif-sur-Yvette

Thursday April 14th 11:00  

   “Nuclear self-assembly following vertebrate mitosis”

Alex VON APPEN

See calendar for abstract

Contact: Sophie Zinn-Justin <sophie.zinn@i2bc.paris-saclay.fr>

B3S Department External Seminar

 Auditorium Building 21, Gif-sur-Yvette

Monday May 23rd 11:00  

  

PARP inhibitors Mechanism of Actions and Cancer Treatment Paradigms

Eli ROTHENBERG

New York University School of Medicine

Contact: Jean-Baptiste Charbonnier <jean-baptiste.charbonnier@i2bc.paris-saclay.fr>

Upcoming …  

Virology Department External Seminar

 Conference room building 12 and videoconference, CNRS Gif-sur-Yvette*

Thuesday March 14th 11:00 – 12:00    

Host-microbe interactions: infectious diseases and symbiosis Axis

  

 

ATG5 drives an LC3-associated pathway to counter BST2/Tetherin antiviral functions

Dr Delphine Judith

from Université de Paris, Institut Cochin, laboratoire « Interactions Hôte-Virus »

Contact: Audrey Escaltine

* Pass-Sanitaire is required or ask for link

Cytoskeleton club External Seminar

Visioconference

 Dec 14th 11:30 – 12:30

Tuesday December 14th 11.30 a.m.

Clathrin plaques form mechanotransducing platforms

Stéphane Vassilopoulos

Institute of Myology – INSERM-Sorbonne Université U974 – Paris

Contact for link: Christophe Le Clainche (christophe.leclainche@i2bc.paris-saclay.fr)

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