Institute for Integrative Biology of the Cell
September 16th, 2024 by Genome Biology Dept
TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR
TLN468 promotes PTC readthrough by preferentially incorporating specific tRNAs based on the mutation.
September 16th, 2024 by Genome Biology Dept
Prophage induction can facilitate the in vitro dispersal of multicellular Streptomyces structures
Unveiling a new property of bacteriophage-host interaction in the context of multicellular aggregate dynamics – A multidisciplinary study involving three departments from I2BC (Genomes, Microbiology, and Virology) and a team from MICALIS.
September 16th, 2024 by BioCell Dept
Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involvesSAM-dependent signaling and transcription activator Met4
Autophagy has a key protective role under nutrient stresses. The authors unveil in yeast an original mechanism of induction of autophagy under sulfur deprivation that requires the transcription activator Met4 and involves S-adenosylmethionine as signaling molecule.
September 16th, 2024 by B3S Dept
Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP
Early Steps of DNA Recombination: AlphaFold2 breaks a lock.
September 16th, 2024 by Microbio Dept
Impact of the Deletion of Genes of the Nitrogen Metabolism on Triacylglycerol, Cardiolipin and Actinorhodin Biosynthesis in Streptomyces coelicolor
Analysis of the consequences of the deletion of genes involved in nitrogen metabolism on the content of phospholipids or of storage lipids of Streptomyces coelicolor illustrates the complex links exiting between carbon, nitrogen and phosphate metabolisms.
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