Institute for Integrative Biology of the Cell
July 26th, 2024 by BioCell Dept
Gradual ER calcium depletion induces a progressive and reversible UPR signaling
The UPR sensors show high plasticity in sensing physiological alterations by closely reporting the variations in ER Ca2+ levels. Through this mechanisms cells could rapidly adapt stress response signaling pathways to variations in ER homeostasis
July 26th, 2024 by Genome Biology Dept
Acinetobacter baumannii satellite phage Aci01-2-Phanie depends on a helper myophage for its multiplication
Phanie is a phi-29 like phage that protects its genome inside non-infectious podovirus-like particles, requiring acquisition of the tail from a myovirus helper for production of infectious chimeras.
July 26th, 2024 by Microbio Dept
SYNTERUPTOR : mining genomic islands for non-classical specialized metabolite gene clusters
In search of the hidden gene cluster: Synteruptor, a new tool for identifying bacterial genomic islands and exploring their content in the quest for new specialized metabolism gene clusters.
July 26th, 2024 by B3S Dept
BRCA2 stabilizes DMC1 nucleoprotein filaments in meiosis
To repair programmed double-strand breaks in meiosis, the DNA repair protein BRCA2 binds to the recombinase DMC1 either monomeric or assembled on single-stranded DNA through two different interfaces, and stabilizes DMC1 nucleoprotein filaments.
July 26th, 2024 by Genome Biology Dept
A tumor suppressor that generates subnucleosomes
Researchers from the I2BC, the CNRGH (CEA, National Center of Human Genomics Research), and the University of Edinburgh have revealed how the BAF chromatin remodeler changes the structure and accessibility of genetic material by producing subnucleosomal particles. These findings are published in Nature Structural and Molecular Biology.
It’s happening at 
takes part in
