Institute for Integrative Biology of the Cell

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BAYAN CONSTANTINESCO MICROBIO

february 13th, 2025 by MicroBiology Dept

Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria.

In vitro reconstitution of bacterial protein mycoloylation.

GROGNET GENOMES

february 13th, 2025 by Genome Biology Dept

Genetic differentiation in the MAT-proximal region is not sufficient for suppressing recombination in Podospora anserina

A large genomic region in Podospora anserina remains entirely devoid of crossovers, despite being fully colinear.

DAUTREAUX B3S

february 13th, 2025 by B3S Dept

Complete description of the biosynthetic process of [2Fe-2S] clusters

Iron-sulfur clusters are essential metallocofactors providing catalytic activities to a multitude of enzymes and proteins. Here, we report a comprehensive picture of their assembly mechanism, showing that it relies on the formation of [1Fe-1S] precursors fused into [2Fe-2S] clusters upon dimerization of the scaffold protein.

MENETREY B3S

february 13th, 2025 by B3S Dept

The Asgard archaeal origins of Arf family GTPases involved in eukaryotic organelle dynamics

How did the endomembrane system, unique to eukaryotes, emerge from their prokaryotic ancestors? We report that Arf proteins, which are crucial regulators of membrane dynamics in eukaryotes, originated in the archaeal ancestor of eukaryotes, the Asgard Archaea.

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