Interactions and assembly mechanisms
of proteins and peptides

Publications

Tripathi, Neha, Florent Saudrais, Mona Rysak, Laura Pieri, Serge Pin, Guido Roma, Jean-Philippe Renault, and Yves Boulard. 2024. “Exploring the Interaction of Human α-Synuclein with Polyethylene Nanoplastics: Insights from Computational Modeling and Experimental Corroboration.” Biomacromolecules, October. https://doi.org/10.1021/acs.biomac.4c00918.
Schvartz, Marion, Florent Saudrais, Yves Boulard, Jean-Philippe Renault, Céline Henry, Stéphane Chédin, Serge Pin, and Jean-Christophe Aude. 2024. “Dual Fractions Proteomic Analysis of Silica Nanoparticle Interactions with Protein Extracts.” Materials (Basel, Switzerland) 17 (19): 4909. https://doi.org/10.3390/ma17194909.
Royet, Adrien, Rémi Ruedas, Laetitia Gargowitsch, Virginie Gervais, Johann Habersetzer, Laura Pieri, Malika Ouldali, et al. 2024. “Nonstructural Protein 4 of Human Norovirus Self-Assembles into Various Membrane-Bridging Multimers.” The Journal of Biological Chemistry, August, 107724. https://doi.org/10.1016/j.jbc.2024.107724.
Ferrié, Martin, Virginie Alexandre, Claire Montpellier, Peggy Bouquet, Thibault Tubiana, Léa Mézière, Maliki Ankavay, et al. 2024. “The AP-1 Adaptor Complex Is Essential for Intracellular Trafficking of the ORF2 Capsid Protein and Assembly of Hepatitis E Virus.” Cellular and Molecular Life Sciences: CMLS 81 (1): 335. https://doi.org/10.1007/s00018-024-05367-0.
Saudrais, Florent, Marion Schvartz, Jean-Philippe Renault, Jorge Vieira, Stéphanie Devineau, Jocelyne Leroy, Olivier Taché, Yves Boulard, and Serge Pin. 2024. “The Impact of Virgin and Aged Microstructured Plastics on Proteins: The Case of Hemoglobin Adsorption and Oxygenation.” International Journal of Molecular Sciences 25 (13): 7047. https://doi.org/10.3390/ijms25137047.
Ruedas, Rémi, Rémi Vuillemot, Thibault Tubiana, Jean-Marie Winter, Laura Pieri, Ana-Andreea Arteni, Camille Samson, Slavica Jonic, Magali Mathieu, and Stéphane Bressanelli. 2024. “Structure and Conformational Variability of the HER2-Trastuzumab-Pertuzumab Complex.” Journal of Structural Biology 216 (2): 108095. https://doi.org/10.1016/j.jsb.2024.108095.
Babot, Marion, Yves Boulard, Samira Agouda, Laura Pieri, Sonia Fieulaine, Stéphane Bressanelli, and Virginie Gervais. 2024. “Oligomeric Assembly of the C-Terminal and Transmembrane Region of SARS-CoV-2 Nsp3.” Journal of Virology, March, e0157523. https://doi.org/10.1128/jvi.01575-23.
Rossier, Ombeline, Cécile Labarre, Anne Lopes, Monique Auberdiac, Kevin Tambosco, Daniel Delaruelle, Hakima Abes, et al. 2024. “Genome Sequence of PSonyx, a Singleton Bacteriophage Infecting Corynebacterium Glutamicum.” Microbiology Resource Announcements, January, e0115523. https://doi.org/10.1128/mra.01155-23.
Babot, Marion, Stéphane Bressanelli, and Virginie Gervais. 2024. “[Self-assembly of the C-terminal and transmembrane region of the SARS-CoV-2 protein nsp3].” Medecine Sciences: M/S 40 (6–7): 498–500. https://doi.org/10.1051/medsci/2024067.
Bohl, Jan, Mohammed Moudjou, Laetitia Herzog, Fabienne Reine, Fiona Sailler, Hannah Klute, Frederic Halgand, et al. 2023. “The Smallest Infectious Substructure Encoding the Prion Strain Structural Determinant Revealed by Spontaneous Dissociation of Misfolded Prion Protein Assemblies.” Journal of Molecular Biology, September, 168280. https://doi.org/10.1016/j.jmb.2023.168280.
Steunou, Anne-Soisig, Marion Babot, Anne Durand, Marie-Line Bourbon, Sylviane Liotenberg, Guylaine Miotello, Jean Armengaud, and Soufian Ouchane. 2023. “Discriminating Susceptibility of Xanthine Oxidoreductase Family to Metals.” Microbiology Spectrum, July, e0481422. https://doi.org/10.1128/spectrum.04814-22.
Kra, Kalouna, Siyu Li, Laetitia Gargowitsch, Jéril Degrouard, Javier Pérez, Roya Zandi, Stéphane Bressanelli, and Guillaume Tresset. 2023. “Energetics and Kinetic Assembly Pathways of Hepatitis B Virus Capsids in the Presence of Antivirals.” ACS Nano, June. https://doi.org/10.1021/acsnano.3c03595.
Schvartz, Marion, Florent Saudrais, Stéphanie Devineau, Stéphane Chédin, Frédéric Jamme, Jocelyne Leroy, Karol Rakotozandriny, et al. 2023. “Role of the Protein Corona in the Colloidal Behavior of Microplastics.” Langmuir: The ACS Journal of Surfaces and Colloids, March. https://doi.org/10.1021/acs.langmuir.2c03237.
Schvartz, Marion, Florent Saudrais, Stéphanie Devineau, Jean-Christophe Aude, Stéphane Chédin, Céline Henry, Aarón Millán-Oropeza, et al. 2023. “A Proteome Scale Study Reveals How Plastic Surfaces and Agitation Promote Protein Aggregation.” Scientific Reports 13 (1): 1227. https://doi.org/10.1038/s41598-023-28412-7.
Fieulaine, Sonia, Thibault Tubiana, and Stéphane Bressanelli. 2023. “De Novo Modelling of HEV Replication Polyprotein: Five-Domain Breakdown and Involvement of Flexibility in Functional Regulation.” Virology 578 (January):128–40. https://doi.org/10.1016/j.virol.2022.12.002.
Fieulaine, Sonia, Thibault Tubiana, and Stéphane Bressanelli. 2023. “Hepatitis E Virus RNA Replication Polyprotein: Taking Structural Biology Seriously.” Frontiers in Microbiology 14:1254741. https://doi.org/10.3389/fmicb.2023.1254741.
Bentaleb, Cyrine, Kévin Hervouet, Claire Montpellier, Charline Camuzet, Martin Ferrié, Julien Burlaud-Gaillard, Stéphane Bressanelli, et al. 2022. “The Endocytic Recycling Compartment Serves as a Viral Factory for Hepatitis E Virus.” Cellular and Molecular Life Sciences 79 (12): 615. https://doi.org/10.1007/s00018-022-04646-y.
Su, Dan-Dan, Virginie Gervais, Sebastien Ulrich, and Mihail Barboiu. 2022. “Complexation Preferences of Dynamic Constitutional Frameworks as Adaptive Gene Vectors.” Chemistry – A European Journal n/a (n/a). https://doi.org/10.1002/chem.202203062.
Su, Dan-Dan, Karim Aissou, Yan Zhang, Virginie Gervais, Sebastien Ulrich, and Mihail Barboiu. 2022. “Squalene–Polyethyleneimine–Dynamic Constitutional Frameworks Enhancing the Enzymatic Activity of Carbonic Anhydrase.” Catalysis Science & Technology 12 (10): 3094–3101. https://doi.org/10.1039/D1CY02290C.
Lauressergues, Dominique, Mélanie Ormancey, Bruno Guillotin, Hélène San Clemente, Laurent Camborde, Carine Duboé, Sabine Tourneur, et al. 2022. “Characterization of Plant MicroRNA-Encoded Peptides (MiPEPs) Reveals Molecular Mechanisms from the Translation to Activity and Specificity.” Cell Reports 38 (6). https://doi.org/10.1016/j.celrep.2022.110339.
Pieri, Laura, Fengbin Wang, Ana-Andreea Arteni, Matthijn Vos, Jean-Marie Winter, Marie-Hélène Le Du, Franck Artzner, et al. 2022. “Atomic Structure of Lanreotide Nanotubes Revealed by Cryo-EM.” Proceedings of the National Academy of Sciences 119 (4). https://doi.org/10.1073/pnas.2120346119.
Chaker, Ziyad, Pierre Chervy, Yves Boulard, Stéphane Bressanelli, Pascal Retailleau, Maité Paternostre, and Thibault Charpentier. 2021. “Systematic Method for the Exploration, Representation, and Classification of the Diphenylalanine Solvatomorphic Space.” The Journal of Physical Chemistry. B 125 (33): 9454–66. https://doi.org/10.1021/acs.jpcb.1c04203.
Marichal, Laurent, Laetitia Gargowitsch, Rafael Leite Rubim, Christina Sizun, Kalouna Kra, Stéphane Bressanelli, Yinan Dong, Sanaz Panahandeh, Roya Zandi, and Guillaume Tresset. 2021. “Relationships between RNA Topology and Nucleocapsid Structure in a Model Icosahedral Virus.” Biophysical Journal, August, S0006-3495(21)00687-1. https://doi.org/10.1016/j.bpj.2021.08.021.
Lecoq, Lauriane, Shishan Wang, Marie Dujardin, Peter Zimmermann, Leonard Schuster, Marie-Laure Fogeron, Mathilde Briday, et al. 2021. “A Pocket-Factor-Triggered Conformational Switch in the Hepatitis B Virus Capsid.” Proceedings of the National Academy of Sciences of the United States of America 118 (17): e2022464118. https://doi.org/10.1073/pnas.2022464118.
Boulard, Yves, and Stéphane Bressanelli. 2021. “Recapitulating Trafficking of Nucleosides Into the Active Site of Polymerases of RNA Viruses: The Challenge and the Prize.” Frontiers in Medical Technology 3. https://www.frontiersin.org/article/10.3389/fmedt.2021.705875.
Chevreuil, Maelenn, Lauriane Lecoq, Shishan Wang, Laetitia Gargowitsch, Naïma Nhiri, Eric Jacquet, Thomas Zinn, Sonia Fieulaine, Stéphane Bressanelli, and Guillaume Tresset. 2020. “Nonsymmetrical Dynamics of the HBV Capsid Assembly and Disassembly Evidenced by Their Transient Species.” The Journal of Physical Chemistry B 124 (45): 9987–95. https://doi.org/10.1021/acs.jpcb.0c05024.
Habersetzer, Johann, Mohamed Debbah, Marie-Laure Fogeron, Anja Böckmann, Stéphane Bressanelli, and Sonia Fieulaine. 2020. “In Vitro Translation of Virally-Encoded Replication Polyproteins to Recapitulate Polyprotein Maturation Processes.” Protein Expression and Purification 175 (November):105694. https://doi.org/10.1016/j.pep.2020.105694.
Fieulaine, Sonia, Martin D. Witte, Christopher S. Theile, Maya Ayach, Hidde L. Ploegh, Isabelle Jupin, and Stéphane Bressanelli. 2020. “Turnip Yellow Mosaic Virus Protease Binds Ubiquitin Suboptimally to Fine-Tune Its Deubiquitinase Activity.” Journal of Biological Chemistry 295 (40): 13769–83. https://doi.org/10.1074/jbc.RA120.014628.
Sanchez-Guzman, Daniel, Gaël Giraudon--Colas, Laurent Marichal, Yves Boulard, Frank Wien, Jéril Degrouard, Armelle Baeza-Squiban, Serge Pin, Jean Philippe Renault, and Stéphanie Devineau. 2020. “In Situ Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation.” ACS Nano 14 (7): 9073–88. https://doi.org/10.1021/acsnano.0c04165.
Marichal, Laurent, Jeril Degrouard, Anouchka Gatin, Nolwenn Raffray, Jean-Christophe Aude, Yves Boulard, Sophie Combet, et al. 2020. “From Protein Corona to Colloidal Self-Assembly: The Importance of Protein Size in Protein-Nanoparticle Interactions.” Langmuir: The ACS Journal of Surfaces and Colloids 36 (28): 8218–30. https://doi.org/10.1021/acs.langmuir.0c01334.
Omrane, Mohyeddine, Amanda Souza Camara, Cyntia Taveneau, Nassima Benzoubir, Thibault Tubiana, Jinchao Yu, Raphaël Guérois, et al. 2020. “Septin 9 Has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity.” IScience 13 (May):138–53. https://doi.org/10.1016/j.isci.2019.02.015.
Lafosse, Marine, Elise Cartier, Kathleen Solmont, Julie Rivollier, Djamille Azazna, Pierre Thuéry, Yves Boulard, et al. 2020. “Clickable Bambusurils to Access Multivalent Architectures.” Organic Letters 22 (8): 3099–3103. https://doi.org/10.1021/acs.orglett.0c00856.
Bolte, Susanne, Elodie Marcon, Mélanie Jaunario, Lucas Moyet, Marie-Thérèse Paternostre, Marcel Kuntz, and Anja Krieger-Liszkay. 2020. “Dynamics of the Localization of the Plastid Terminal Oxidase PTOX inside the Chloroplast.” Journal of Experimental Botany 71 (9): 2661–69. https://doi.org/10.1093/jxb/eraa074.
Marichal, Laurent, Geraldine Klein, Jean Armengaud, Yves Boulard, Stephane Chedin, Jean Labarre, Serge Pin, Jean-Philippe Renault, and Jean-Christophe Aude. 2020. “Protein Corona Composition of Silica Nanoparticles in Complex Media: Nanoparticle Size Does Not Matter.” Nanomaterials 10 (2): 240. https://doi.org/10.3390/nano10020240.
Marichal, Laurent, Gaël Giraudon--Colas, Fabrice Cousin, Antoine Thill, Jean Labarre, Yves Boulard, Jean-Christophe Aude, Serge Pin, and Jean Philippe Renault. 2019. “Protein–Nanoparticle Interactions: What Are the Protein–Corona Thickness and Organization?” Langmuir 35 (33): 10831–37. https://doi.org/10.1021/acs.langmuir.9b01373.
Chervy, Pierre, Cristina Petcut, Damien Rault, Cristelle Meriadec, Thomas Bizien, Keinny François, Joel Richard, et al. 2019. “Organic Nanoscrolls from Electrostatic Interactions between Peptides and Lipids: Assembly Steps and Structure.” Langmuir 35 (32): 10648–57. https://doi.org/10.1021/acs.langmuir.9b01542.
Ben Ouirane, Kaouther, Yves Boulard, and Stéphane Bressanelli. 2019. “The Hepatitis C Virus RNA-Dependent RNA Polymerase Directs Incoming Nucleotides to Its Active Site through Magnesium-Dependent Dynamics within Its F Motif.” The Journal of Biological Chemistry 294 (19): 7573–87. https://doi.org/10.1074/jbc.RA118.005209.
Tubiana, Thibault, Jean-Charles Carvaillo, Yves Boulard, and Stephane Bressanelli. 2018. “TTClust: A Versatile Molecular Simulation Trajectory Clustering Program with Graphical Summaries.” Journal of Chemical Information and Modeling 58 (11): 2178–82. https://doi.org/10.1021/acs.jcim.8b00512.
Chevreuil, Maelenn, Didier Law-Hine, Jingzhi Chen, Stéphane Bressanelli, Sophie Combet, Doru Constantin, Jéril Degrouard, Johannes Möller, Mehdi Zeghal, and Guillaume Tresset. 2018. “Nonequilibrium Self-Assembly Dynamics of Icosahedral Viral Capsids Packaging Genome or Polyelectrolyte.” Nature Communications 9 (1): 3071. https://doi.org/10.1038/s41467-018-05426-8.
Lecoq, Lauriane, Shishan Wang, Thomas Wiegand, Stéphane Bressanelli, Michael Nassal, Beat H. Meier, and Anja Böckmann. 2018. “Localizing Conformational Hinges by NMR: Where Do Hepatitis B Virus Core Proteins Adapt for Capsid Assembly?” Chemphyschem: A European Journal of Chemical Physics and Physical Chemistry 19 (11): 1336–40. https://doi.org/10.1002/cphc.201800211.
Marichal, Laurent, Jean-Philippe Renault, Stéphane Chédin, Gilles Lagniel, Géraldine Klein, Jean-Christophe Aude, Carine Tellier-Lebegue, et al. 2018. “Importance of Post-Translational Modifications in the Interaction of Proteins with Mineral Surfaces: The Case of Arginine Methylation and Silica Surfaces.” Langmuir: The ACS Journal of Surfaces and Colloids 34 (18): 5312–22. https://doi.org/10.1021/acs.langmuir.8b00752.
Lecoq, Lauriane, Shishan Wang, Thomas Wiegand, Stéphane Bressanelli, Michael Nassal, Beat H. Meier, and Anja Böckmann. 2018. “Solid-State [13C-15N] NMR Resonance Assignment of Hepatitis B Virus Core Protein.” Biomolecular NMR Assignments 12 (1): 205–14. https://doi.org/10.1007/s12104-018-9810-y.
Grzela, Renata, Julien Nusbaum, Sonia Fieulaine, Francesco Lavecchia, Michel Desmadril, Naima Nhiri, Alain Van Dorsselaer, et al. 2018. “Peptide Deformylases from Vibrio Parahaemolyticus Phage and Bacteria Display Similar Deformylase Activity and Inhibitor Binding Clefts.” Biochimica Et Biophysica Acta 1866 (2): 348–55. https://doi.org/10.1016/j.bbapap.2017.10.007.
Jupin, Isabelle, Maya Ayach, Lucile Jomat, Sonia Fieulaine, and Stéphane Bressanelli. 2017. “A Mobile Loop near the Active Site Acts as a Switch between the Dual Activities of a Viral Protease/Deubiquitinase.” Edited by Richard J. Kuhn. PLOS Pathogens 13 (11): e1006714. https://doi.org/10.1371/journal.ppat.1006714.
Doerflinger, Sylvie Y., Mirko Cortese, Inés Romero-Brey, Zach Menne, Thibault Tubiana, Christian Schenk, Peter A. White, et al. 2017. “Membrane Alterations Induced by Nonstructural Proteins of Human Norovirus.” PLoS Pathogens 13 (10): e1006705. https://doi.org/10.1371/journal.ppat.1006705.
Grzela, Renata, Julien Nusbaum, Sonia Fieulaine, Francesco Lavecchia, Willy V. Bienvenut, Cyril Dian, Thierry Meinnel, and Carmela Giglione. 2017. “The C-Terminal Residue of Phage Vp16 PDF, the Smallest Peptide Deformylase, Acts as an Offset Element Locking the Active Conformation.” Scientific Reports 7 (1): 11041. https://doi.org/10.1038/s41598-017-11329-3.
Mandal, Pravat K., Deepika Shukla, Varan Govind, Yves Boulard, and Lars Ersland. 2017. “Glutathione Conformations and Its Implications for in Vivo Magnetic Resonance Spectroscopy.” Journal of Alzheimer’s Disease: JAD 59 (2): 537–41. https://doi.org/10.3233/JAD-170350.
Baquero, Eduard, Aurélie A Albertini, Hélène Raux, Abbas Abou‐Hamdan, Elisabetta Boeri‐Erba, Malika Ouldali, Linda Buonocore, et al. 2017. “Structural Intermediates in the Fusion‐associated Transition of Vesiculovirus Glycoprotein.” The EMBO Journal 36 (5): 679–92. https://doi.org/10.15252/embj.201694565.
Fieulaine, Sonia, Rodolphe Alves de Sousa, Laure Maigre, Karim Hamiche, Mickael Alimi, Jean-Michel Bolla, Abbass Taleb, et al. 2017. “Corrigendum: A Unique Peptide Deformylase Platform to Rationally Design and Challenge Novel Active Compounds.” Scientific Reports 7 (January):39365. https://doi.org/10.1038/srep39365.
Karakas, Esra, Cyntia Taveneau, Stéphane Bressanelli, Massimo Marchi, Bruno Robert, and Stéphane Abel. 2017. “Derivation of Original RESP Atomic Partial Charges for MD Simulations of the LDAO Surfactant with AMBER: Applications to a Model of Micelle and a Fragment of the Lipid Kinase PI4KA.” Journal of Biomolecular Structure and Dynamics 35 (1): 159–81. https://doi.org/10.1080/07391102.2015.1135822.
Scroll to Top