Programmed genome
rearrangements

Publications

Miró-Pina, Caridad, Olivia Charmant, Takayuki Kawaguchi, Daniel Holoch, Audrey Michaud, Isadora Cohen, Adeline Humbert, et al. 2022. “Paramecium Polycomb Repressive Complex 2 Physically Interacts with the Small RNA-Binding PIWI Protein to Repress Transposable Elements.” Developmental Cell, April. https://doi.org/10.1016/j.devcel.2022.03.014.
Gnan, Stefano, Melody Matelot, Marion Weiman, Olivier Arnaiz, Frederic Guerin, Linda Sperling, Mireille Betermier, Claude Thermes, Chun-Long Chen, and Sandra Duharcourt. 2022. “GC Content but Not Nucleosome Positioning Directly Contributes to Intron-Splicing Efficiency in Paramecium.” Genome Research, March, gr.276125.121. https://doi.org/10.1101/gr.276125.121.
Owsian, Dawid, Julita Gruchota, Olivier Arnaiz, and Jacek K Nowak. 2022. “The Transient Spt4-Spt5 Complex as an Upstream Regulator of Non-Coding RNAs during Development.” Nucleic Acids Research, February, gkac106. https://doi.org/10.1093/nar/gkac106.
Sellis, Diamantis, Frédéric Guérin, Olivier Arnaiz, Walker Pett, Emmanuelle Lerat, Nicole Boggetto, Sascha Krenek, et al. 2021. “Massive Colonization of Protein-Coding Exons by Selfish Genetic Elements in Paramecium Germline Genomes.” PLOS Biology 19 (7): e3001309. https://doi.org/10.1371/journal.pbio.3001309.
Guérineau, Marc, Luiza Bessa, Séverine Moriau, Ewen Lescop, François Bontems, Nathalie Mathy, Eric Guittet, Julien Bischerour, Mireille Bétermier, and Nelly Morellet. 2021. “The Unusual Structure of the PiggyMac Cysteine-Rich Domain Reveals Zinc Finger Diversity in PiggyBac-Related Transposases.” Mobile DNA 12 (1): 12. https://doi.org/10.1186/s13100-021-00240-4.
Sawka-Gądek, Natalia, Alexey Potekhin, Deepankar Pratap Singh, Inessa Grevtseva, Olivier Arnaiz, Simon Penel, Linda Sperling, et al. 2020. “Evolutionary Plasticity of Mating-Type Determination Mechanisms in Paramecium Aurelia Sibling Species.” Genome Biology and Evolution 13 (2): evaa258. https://doi.org/10.1093/gbe/evaa258.
Gogendeau, Delphine, Michel Lemullois, Pierrick Le Borgne, Manon Castelli, Anne Aubusson-Fleury, Olivier Arnaiz, Jean Cohen, et al. 2020. “MKS-NPHP Module Proteins Control Ciliary Shedding at the Transition Zone.” PLoS Biology 18 (3): e3000640. https://doi.org/10.1371/journal.pbio.3000640.
Sperling, Linda. 2020. “Janine Beisson, Pioneer of Cytoplasmic Heredity (June 9, 1931, Saïda – August 30, 2020, Megève).” Protist 171 (6): 125769. https://doi.org/10.1016/j.protis.2020.125769.
Vanssay, Augustin de, Amandine Touzeau, Olivier Arnaiz, Andrea Frapporti, Jamie Phipps, and Sandra Duharcourt. 2020. “The Paramecium Histone Chaperone Spt16-1 Is Required for Pgm Endonuclease Function in Programmed Genome Rearrangements.” PLoS Genetics 16 (7): e1008949. https://doi.org/10.1371/journal.pgen.1008949.
Abello, Arthur, Vinciane Régnier, Olivier Arnaiz, Romain Le Bars, Mireille Bétermier, and Julien Bischerour. 2020. “Functional Diversification of Paramecium Ku80 Paralogs Safeguards Genome Integrity during Precise Programmed DNA Elimination.” PLoS Genetics 16 (4): e1008723. https://doi.org/10.1371/journal.pgen.1008723.
Bétermier, Mireille, Valérie Borde, and Jean-Pierre de Villartay. 2020. “Coupling DNA Damage and Repair: An Essential Safeguard during Programmed DNA Double-Strand Breaks?” Trends in Cell Biology 30 (2): 87–96. https://doi.org/10.1016/j.tcb.2019.11.005.
Arnaiz, Olivier, Eric Meyer, and Linda Sperling. 2020. “ParameciumDB 2019: Integrating Genomic Data across the Genus for Functional and Evolutionary Biology.” Nucleic Acids Research 48 (D1): D599–605. https://doi.org/10.1093/nar/gkz948.
Frapporti, Andrea, Caridad Miró Pina, Olivier Arnaiz, Daniel Holoch, Takayuki Kawaguchi, Adeline Humbert, Evangelia Eleftheriou, et al. 2019. “The Polycomb Protein Ezl1 Mediates H3K9 and H3K27 Methylation to Repress Transposable Elements in Paramecium.” Nature Communications 10 (1): 2710. https://doi.org/10.1038/s41467-019-10648-5.
Nekrasova, Irina, Vera Nikitashina, Simran Bhullar, Olivier Arnaiz, Deepankar P. Singh, Eric Meyer, and Alexey Potekhin. 2019. “Loss of a Fragile Chromosome Region Leads to the Screwy Phenotype in Paramecium Tetraurelia.” Genes 10 (7): 513. https://doi.org/10.3390/genes10070513.
Godau, Julia, Lorenza P. Ferretti, Anika Trenner, Emeline Dubois, Christine von Aesch, Antoine Marmignon, Lauriane Simon, et al. 2019. “Identification of a Miniature Sae2/Ctp1/CtIP Ortholog from Paramecium Tetraurelia Required for Sexual Reproduction and DNA Double-Strand Break Repair.” DNA Repair 77: 96–108. https://doi.org/10.1016/j.dnarep.2019.03.011.
Bhullar, Simran, Cyril Denby Wilkes, Olivier Arnaiz, Mariusz Nowacki, Linda Sperling, and Eric Meyer. 2018. “A Mating-Type Mutagenesis Screen Identifies a Zinc-Finger Protein Required for Specific DNA Excision Events in Paramecium.” Nucleic Acids Research 46 (18): 9550–62. https://doi.org/10.1093/nar/gky772.
Bischerour, Julien, Simran Bhullar, Cyril Denby Wilkes, Vinciane Régnier, Nathalie Mathy, Emeline Dubois, Aditi Singh, et al. 2018. “Six Domesticated PiggyBac Transposases Together Carry out Programmed DNA Elimination in Paramecium.” ELife 7: e37927. https://doi.org/10.7554/eLife.37927.
Morellet, Nelly, Xianghong Li, Silke A. Wieninger, Jennifer L. Taylor, Julien Bischerour, Séverine Moriau, Ewen Lescop, et al. 2018. “Sequence-Specific DNA Binding Activity of the Cross-Brace Zinc Finger Motif of the PiggyBac Transposase.” Nucleic Acids Research 46 (5): 2660–77. https://doi.org/10.1093/nar/gky044.
Shi, Lei, France Koll, Olivier Arnaiz, and Jean Cohen. 2018. “The Ciliary Protein IFT57 in the Macronucleus of Paramecium.” The Journal of Eukaryotic Microbiology 65 (1): 12–27. https://doi.org/10.1111/jeu.12423.
Arnaiz, Olivier, Erwin Van Dijk, Mireille Bétermier, Maoussi Lhuillier-Akakpo, Augustin de Vanssay, Sandra Duharcourt, Erika Sallet, Jérôme Gouzy, and Linda Sperling. 2017. “Improved Methods and Resources for Paramecium Genomics: Transcription Units, Gene Annotation and Gene Expression.” BMC Genomics 18 (1): 483. https://doi.org/10.1186/s12864-017-3887-z.
Dubois, Emeline, Nathalie Mathy, Vinciane Régnier, Julien Bischerour, Céline Baudry, Raphaëlle Trouslard, and Mireille Bétermier. 2017. “Multimerization Properties of PiggyMac, a Domesticated PiggyBac Transposase Involved in Programmed Genome Rearrangements.” Nucleic Acids Research 45 (6): 3204–16. https://doi.org/10.1093/nar/gkw1359.
Maliszewska-Olejniczak, Kamila, Julita Gruchota, Robert Gromadka, Cyril Denby Wilkes, Olivier Arnaiz, Nathalie Mathy, Sandra Duharcourt, Mireille Bétermier, and Jacek K. Nowak. 2015. “TFIIS-Dependent Non-Coding Transcription Regulates Developmental Genome Rearrangements.” PLoS Genetics 11 (7): e1005383. https://doi.org/10.1371/journal.pgen.1005383.
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