Determinants of CrossOver Distribution
across Eukaryotes
Publications
3888256
DECODE
1
chicago-author-date
50
date
desc
year
54816
https://www.i2bc.paris-saclay.fr/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22HPJ4PFA4%22%2C%22library%22%3A%7B%22id%22%3A3888256%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Madec%20et%20al.%22%2C%22parsedDate%22%3A%222026-08-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMadec%2C%20Beno%26%23xEE%3Bt%2C%20Ma%26%23xEB%3Bla%20S%26%23xE9%3Bmery%2C%20Qichao%20Lian%2C%20et%20al.%202026.%20%26%23x201C%3BPolymorphism%20Can%20Extensively%20Reshape%20the%20Genome-Wide%20Crossover%20Landscape%20in%20Arabidopsis%20Thaliana.%26%23x201D%3B%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2017%20%281%29%3A%209304.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-026-76213-z%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-026-76213-z%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Polymorphism%20can%20extensively%20reshape%20the%20genome-wide%20crossover%20landscape%20in%20Arabidopsis%20thaliana%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Beno%5Cu00eet%22%2C%22lastName%22%3A%22Madec%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ma%5Cu00ebla%22%2C%22lastName%22%3A%22S%5Cu00e9mery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qichao%22%2C%22lastName%22%3A%22Lian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohamad%22%2C%22lastName%22%3A%22Yassine%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lo%5Cu00efse%22%2C%22lastName%22%3A%22L%5Cu00e9onard-Moniot%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%5Cu00c9ric%22%2C%22lastName%22%3A%22Espagne%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sophie%22%2C%22lastName%22%3A%22Piquerez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chlo%5Cu00e9%22%2C%22lastName%22%3A%22Girard%22%7D%5D%2C%22abstractNote%22%3A%22Meiotic%20recombination%2C%20via%20the%20formation%20of%20crossovers%20%28COs%29%2C%20re-assorts%20parental%20alleles%20and%20dictate%20which%20traits%20are%20inherited%20together%2C%20or%20not.%20The%20recombination%20rate%20is%20not%20homogeneous%20across%20the%20genome%2C%20and%20uncovering%20the%20causes%20of%20these%20fluctuations%20can%20inform%20our%20understanding%20of%20recombination%20and%20genome%20evolution.%20In%20this%20study%20we%20show%20that%20presence%20of%20sequence%20divergence%20%28polymorphism%29%20between%20homologous%20chromosomes%20can%20dictate%20where%20crossovers%20are%20formed%20in%20Arabidopsis%20thaliana.%20Indeed%2C%20presence%20of%20polymorphism%20increases%20the%20local%20recombination%20rate%2C%20turning%20cold%20regions%20of%20the%20genome%20hot.%20This%20relocation%20occurs%20at%20the%20expense%20of%20non-polymorphic%20regions%2C%20which%20become%20colder.%20This%20global%20overhaul%20of%20the%20CO%20landscape%20is%20dependent%20on%20the%20mismatch%20repair%20%28MMR%29%20machinery.%20Our%20data%20suggests%20that%20MMR%20has%20a%20pro-CO%20role%2C%20driving%20COs%20to%20regions%20of%20the%20genome%20where%20it%20could%20detect%20sequence%20differences%20between%20homologous%20chromosomes.%20Our%20study%20demonstrates%20that%20polymorphism%20can%20be%20a%20major%20recombination%20driver%20in%20A.%20thaliana.%22%2C%22date%22%3A%222026-08-01%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-026-76213-z%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2242669675%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%222041-1723%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222026-10-08T10%3A04%3A02Z%22%7D%7D%5D%7D
Madec, Benoît, Maëla Sémery, Qichao Lian, et al. 2026. “Polymorphism Can Extensively Reshape the Genome-Wide Crossover Landscape in Arabidopsis Thaliana.” Nature Communications 17 (1): 9304. https://doi.org/10.1038/s41467-026-76213-z.