Integrative Bio Informatics
KeyTech
The Bioinformatics Platform of I2BC offers access to resources and activities in bioinformatics developed and of use in the unit.
It gathers several tools in the field of comparative analysis of genomes, the study of RNAs and the structural modeling of cellular machineries. The Bioinformatics Platform is located at the heart of the 13 technological platforms of the I2BC, which are members of the National Infrastructures in Biology and Health (FRISBI, FBI, France-Genomics), in order to promote the integration and exploitation of data generated by users.
It offers support services to facilitate and improve the processing of NGS sequencing, proteomics or biophysics data and organizes bioinformatics training in close collaboration with the IFB.
Services, Database and Tools
Access to the I2BC computing infrastructure (calculation, storage, access to general biological data collections, use of bioinformatics softwares).
. Support for scientific projects (expertise, development of workflows, data processing).
. Access to specialized databases, resulting from the scientific expertise of the platform’s host laboratory (proteomic and genomic data mining, bacterial and archaeal genome mining).
. Access to online tools and services, corresponding to the platform’s areas of expertise, via web services, scripts, containers (prediction of protein structures and complexes, Far Homology Prediction, synteny, motifs, . prediction of secondary and tertiary structures in RNA, orthologous genes, orphan enzymes).
. Organization of trainings in bioinformatics.
Examples of tools developed by the institute :
DNA, RNA & Genomes (ex : ParameciumDB (https://paramecium.i2bc.paris-saclay.fr/), CRISPRCas++(https://crisprcas.i2bc.paris-saclay.fr/),
Protein & Proteomes (ex : VIRFAM (http://biodev.cea.fr/virfam/) , NterDB (https://n-terdb.i2bc.paris-saclay.fr/) )
Structural Biology (ex : Interevol (http://biodev.cea.fr/interevol/) )
Evolution & Phylogeny (ex : Synteruptor (http://bim.i2bc.paris-saclay.fr/synteruptor/))
team
Raphaël GUEROIS
Head of Facility
Researcher
Olivier LESPINET
Head of Facility
Researcher
Arnaud MARTEL
Technical Manager
Engineer
Daniel GAUTHERET
Researcher
Claire TOFFANO-NIOCHE
Researcher
Stéphane BRESSANELLI
Researcher
Olivier ARNAIZ
Engineer
Pierre-Albert CHARBIT
Engineer
External funding
IBISA
FranceBioImaging
LabexSPS
Morphoscope
Networks
GDR Imabio
RTMFM
SBCF
ISO 9001-NFX50 900 (Qualité)