Institute for Integrative Biology of the Cell

Bury-Mone - GEN

December 2nd, 2022 by Genome Dept

Ribosomal RNA operons define a central functional compartment in the Streptomyces chromosome
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Ribosomal RNA operon-based evolutionary history in Streptomyces: rrn operons define a functional compartment prone to transcription and are close to pericentric inversions. Towards the existence of functional compartments in bacteria?

Filleur Biocell

December 2nd, 2022 by Cell Biology Dept

Proton exchange by the vacuolar nitrate transporter CLCa is required
for plant growth and nitrogen use efficiency
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CLCa exchange mechanism limits nitrogen use efficicency in plants.

Moris (Viro)

November 18th, 2022 by Virology Dept

Autophagy Receptors in antigen presentation and antiviral T cell immunity
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Autophagy receptor T6BP (TAX1BP1) stabilizes the invariant chain (CD74) and regulates MHC-II molecule (MHC-II) trafficking, thereby favouring the presentation of high affinity peptides to virus-specific CD4+ T cells.

Valerio B3S

November 18th, 2022 by B3S Dept

Artificials proteins, αReps, targeting the SARS-CoV-2 spike as antivirals
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Specific binders targeting the SARS-CoV-2 spike protein were selected from the αRep library. Two combined αRep nanoligands neutralize SARS-CoV-2 variants and reduce infection severity in hamster.

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Upcoming …  

 External Seminar

 Auditorium Building 21, Gif-sur-Yvette

Friday September 16th 2022  11 a.m

Membrane compartmentalization of Ect2/Cyk4/Mklp1 and NuMA/dynein coordinates chromosome separation with cleavage furrow formation

Sachin Kotak

RIndian Institute of Science (IISc), Bangalore, India

Contact: Contact: Anne-Marie Tassin

 Cytoskeleton Club Seminar

 Library Building 34, Gif-sur-Yvette

Friday September 16th 2022  02 p.m.  

The adherens junction α-catenin-vinculin-VASP complex promotes actin assembly

Rayan Said

B3S Department I2BC

Contact:  Christophe Le ClaincheJulie Ménétrey

Upcoming …  

THE SCIENTIFIC AFFAIRS

Edith Wilmart joined I2BC in September 2022 to build up a Scientific Affairs Department and to make the best use of the unit’s potential and structure
the contractual and partnership policy.
Lorena Solarte Fajardo has just joined the scientific affairs as a transfer engineer (business developer).

Scientific Affairs Department will strengthen the academic and industrial partnership policy based on the scientific and technological wealth of the research teams, platforms and
transverse programmes.

November 25th   The "Drug and Technology for Health" Department is part of the CEA's Joliot Institute, as is the I2BC. The aim of the DMTS-I2BC day is to get to know each other and to encourage potential collaborations. Two themes were chosen for this first edition: "Host-Microbe Interactions" and "Molecular Tools for Biology". More informations here

Holy coli: a mouse in the odour of sanctity
Holy coli: a mouse in the odour of sanctity
Informations here

Latest Publications

Calendar

I2BC scientific Axis 1 seminar

 Auditorium Building 21, Gif-sur-Yvette

Thursday April 14th 11:00  

   “Nuclear self-assembly following vertebrate mitosis”

Alex VON APPEN

See calendar for abstract

Contact: Sophie Zinn-Justin <sophie.zinn@i2bc.paris-saclay.fr>

B3S Department External Seminar

 Auditorium Building 21, Gif-sur-Yvette

Monday May 23rd 11:00  

  

PARP inhibitors Mechanism of Actions and Cancer Treatment Paradigms

Eli ROTHENBERG

New York University School of Medicine

Contact: Jean-Baptiste Charbonnier <jean-baptiste.charbonnier@i2bc.paris-saclay.fr>

Upcoming …  

Virology Department External Seminar

 Conference room building 12 and videoconference, CNRS Gif-sur-Yvette*

Thuesday March 14th 11:00 – 12:00    

Host-microbe interactions: infectious diseases and symbiosis Axis

  

 

ATG5 drives an LC3-associated pathway to counter BST2/Tetherin antiviral functions

Dr Delphine Judith

from Université de Paris, Institut Cochin, laboratoire « Interactions Hôte-Virus »

Contact: Audrey Escaltine

* Pass-Sanitaire is required or ask for link

Cytoskeleton club External Seminar

Visioconference

 Dec 14th 11:30 – 12:30

Tuesday December 14th 11.30 a.m.

Clathrin plaques form mechanotransducing platforms

Stéphane Vassilopoulos

Institute of Myology – INSERM-Sorbonne Université U974 – Paris

Contact for link: Christophe Le Clainche (christophe.leclainche@i2bc.paris-saclay.fr)

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