Institute for Integrative Biology of the Cell

february 13th, 2025 by MicroBiology Dept
In vitro reconstitution of bacterial protein mycoloylation.

february 13th, 2025 by Genome Biology Dept
A large genomic region in Podospora anserina remains entirely devoid of crossovers, despite being fully colinear.

february 13th, 2025 by B3S Dept
Iron-sulfur clusters are essential metallocofactors providing catalytic activities to a multitude of enzymes and proteins. Here, we report a comprehensive picture of their assembly mechanism, showing that it relies on the formation of [1Fe-1S] precursors fused into [2Fe-2S] clusters upon dimerization of the scaffold protein.

february 13th, 2025 by B3S Dept
How did the endomembrane system, unique to eukaryotes, emerge from their prokaryotic ancestors? We report that Arf proteins, which are crucial regulators of membrane dynamics in eukaryotes, originated in the archaeal ancestor of eukaryotes, the Asgard Archaea.