Institute for Integrative Biology of the Cell




May 10th, 2022 by Cell Biology Dept

Mitochondria are the powerhouses of cells thanks to the oxidative phosphorylation system partially encoded by a small mitochondrial genome (mtDNA). Miranda et al review our current knowledge on mtDNA expression, associated disease phenotypes, and how mtDNA and nuclear gene expression are coordinated.
April 15th, 2022 by B3S Dept

A region of CPAP, a protein regulating the length of the centrioles, is found to have a tubulin binding mode similar to that of bacterial and fungal peptide-like metabolites which inhibit cell division.
april 15, 2022 by Virology Dept

BHRF1, a multifunctional viral protein expressed during Epstein-Barr virus reactivation, modulates mitochondrial dynamics and induces MT hyperacetylation to escape innate immunity. Moreover, the loss of MT hyperacetylation impedes BHRF1 to initiate mitophagy, which is essential to inhibit the signaling pathway.

Latest News
Mai 2022
- Starting the engine of the powerhouse: mitochondrial transcription and beyond
- Structural convergence between inhibitors and a regulator of microtubule dynamics
- Essential role of hyperacetylated microtubules in innate immunity escape orchestrated by the EBV-encoded BHRF1 protein
- ComFC mediates transport and handling of single-stranded DNA during natural transformation
- Limited solvation of an electron donating tryptophan stabilizes a photoinduced charge-separated state in plant (6-4) photolyase.
Scientific day in memory of Agnès Delahodde Friday 13th May 2022
Upcoming …
PARP inhibitors Mechanism of Actions and Cancer Treatment Paradigms
Eli ROTHENBERG
New York University School of Medicine
Contact: Jean-Baptiste Charbonnier <jean-baptiste.charbonnier@i2bc.paris-saclay.fr>
Latest Publications
Calendar
23rd National Congress on Transposable elements (CNET) July 4th-6th | @scoopit
Read MoreInsights into the photocatalytic cycle highlighted at I2BC | @scoopit
Read MoreFrench Days of Photosynthesis: June 9th-10th | @scoopit
Read MoreA new family of genes coding for the biomineralization of carbonates in cyanobacteria | @scoopit
Read MoreAlex VON APPEN
See calendar for abstract
Contact: Sophie Zinn-Justin <sophie.zinn@i2bc.paris-saclay.fr>
B3S Department External Seminar
Auditorium Building 21, Gif-sur-Yvette
Monday May 23rd 11:00
PARP inhibitors Mechanism of Actions and Cancer Treatment Paradigms
Eli ROTHENBERG
New York University School of Medicine
Contact: Jean-Baptiste Charbonnier <jean-baptiste.charbonnier@i2bc.paris-saclay.fr>
Upcoming …
Virology Department External Seminar
Conference room building 12 and videoconference, CNRS Gif-sur-Yvette*
Thuesday March 14th 11:00 – 12:00


ATG5 drives an LC3-associated pathway to counter BST2/Tetherin antiviral functions
Dr Delphine Judith
from Université de Paris, Institut Cochin, laboratoire « Interactions Hôte-Virus »
Contact: Audrey Escaltine
* Pass-Sanitaire is required or ask for link
Cytoskeleton club External Seminar
Visioconference
Dec 14th 11:30 – 12:30
Tuesday December 14th 11.30 a.m.
Clathrin plaques form mechanotransducing platforms
Stéphane Vassilopoulos
Institute of Myology – INSERM-Sorbonne Université U974 – Paris
Contact for link: Christophe Le Clainche (christophe.leclainche@i2bc.paris-saclay.fr)