Enzymology and non ribosomal peptide biosynthesis

Publications

Croitoru, Anastasia, Morgan Babin, Hannu Myllykallio, Muriel Gondry, and Alexey Aleksandrov. 2021. “Cyclodipeptide Synthases of the NYH Subfamily Recognize TRNA Using an α-Helix Enriched with Positive Residues.” Biochemistry 60 (1): 64–76. https://doi.org/10.1021/acs.biochem.0c00761.
Canu, Nicolas, Carine Tellier, Morgan Babin, Robert Thai, Inès Ajel, Jérôme Seguin, Olivier Cinquin, et al. 2020. “Flexizyme-Aminoacylated Shortened TRNAs Demonstrate That Only the Aminoacylated Acceptor Arms of the Two TRNA Substrates Are Required for Cyclodipeptide Synthase Activity.” Nucleic Acids Research 48 (20): 11615–25. https://doi.org/10.1093/nar/gkaa903.
Bourgeois, Gabrielle, Jérôme Seguin, Morgan Babin, Muriel Gondry, Yves Mechulam, and Emmanuelle Schmitt. 2020. “Structural Basis of the Interaction between Cyclodipeptide Synthases and Aminoacylated TRNA Substrates.” RNA 26 (11): 1589–1602. https://doi.org/10.1261/rna.075184.120.
Le Chevalier, Fabien, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, and Pascal Belin. 2020. “In Vivo Characterization of the Activities of Novel Cyclodipeptide Oxidases: New Tools for Increasing Chemical Diversity of Bioproduced 2,5-Diketopiperazines in Escherichia Coli.” Microbial Cell Factories 19 (1): 178. https://doi.org/10.1186/s12934-020-01432-y.
Canu, Nicolas, Mireille Moutiez, Pascal Belin, and Muriel Gondry. 2020. “Cyclodipeptide Synthases: A Promising Biotechnological Tool for the Synthesis of Diverse 2,5-Diketopiperazines.” Natural Product Reports 37: 312 – 321. https://doi.org/10.1039/c9np00036d.
Witwinowski, Jerzy, Mireille Moutiez, Matthieu Coupet, Isabelle Correia, Pascal Belin, Antonio Ruzzini, Corinne Saulnier, et al. 2019. “Study of Bicyclomycin Biosynthesis in Streptomyces Cinnamoneus by Genetic and Biochemical Approaches.” Scientific Reports 9 (1): 20226. https://doi.org/10.1038/s41598-019-56747-7.
Dubois, Pavlina, Isabelle Correia, Fabien Le Chevalier, Steven Dubois, Isabelle Jacques, Nicolas Canu, Mireille Moutiez, et al. 2019. “Author Correction: Reprogramming Escherichia Coli for the Production of Prenylated Indole Diketopiperazine Alkaloids.” Scientific Reports 9 (1): 15009. https://doi.org/10.1038/s41598-019-51404-5.
Dubois, Pavlina, Isabelle Correia, Fabien Le Chevalier, Steven Dubois, Isabelle Jacques, Nicolas Canu, Mireille Moutiez, et al. 2019. “Reprogramming Escherichia Coli for the Production of Prenylated Indole Diketopiperazine Alkaloids.” Scientific Reports 9 (1): 9208. https://doi.org/10.1038/s41598-019-45519-y.
Bourgeois, Gabrielle, Jérôme Seguin, Morgan Babin, Pascal Belin, Mireille Moutiez, Yves Mechulam, Muriel Gondry, and Emmanuelle Schmitt. 2018. “Structural Basis for Partition of the Cyclodipeptide Synthases into Two Subfamilies.” Journal of Structural Biology 203 (1): 17–26. https://doi.org/10.1016/j.jsb.2018.03.001.
Schmitt, Emmanuelle, Gabrielle Bourgeois, Muriel Gondry, and Alexey Aleksandrov. 2018. “Cyclization Reaction Catalyzed by Cyclodipeptide Synthases Relies on a Conserved Tyrosine Residue.” Scientific Reports 8 (1): 7031. https://doi.org/10.1038/s41598-018-25479-5.
Canu, Nicolas, Pascal Belin, Robert Thai, Isabelle Correia, Olivier Lequin, Jérôme Seguin, Mireille Moutiez, and Muriel Gondry. 2018. “Incorporation of Non-Canonical Amino Acids into 2,5-Diketopiperazines by Cyclodipeptide Synthases.” Angewandte Chemie (International Ed. in English) 57 (12): 3118–22. https://doi.org/10.1002/anie.201712536.
Gondry, Muriel, Isabelle B. Jacques, Robert Thai, Morgan Babin, Nicolas Canu, Jérôme Seguin, Pascal Belin, Jean-Luc Pernodet, and Mireille Moutiez. 2018. “A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes.” Frontiers in Microbiology 9: 46. https://doi.org/10.3389/fmicb.2018.00046.
Tellier-Lebegue, Carine, Eléa Dizet, Emilie Ma, Xavier Veaute, Eric Coïc, Jean-Baptiste Charbonnier, and Laurent Maloisel. 2017. “The Translesion DNA Polymerases Pol ζ and Rev1 Are Activated Independently of PCNA Ubiquitination upon UV Radiation in Mutants of DNA Polymerase δ.” Edited by Sue Jinks-Robertson. PLOS Genetics 13 (12): e1007119. https://doi.org/10.1371/journal.pgen.1007119.
Malabirade, Antoine, Javier Morgado-Brajones, Sylvain Trépout, Frank Wien, Ileana Marquez, Jérôme Seguin, Sergio Marco, Marisela Velez, and Véronique Arluison. 2017. “Publisher Correction: Membrane Association of the Bacterial Riboregulator Hfq and Functional Perspectives.” Scientific Reports 7 (1): 15651. https://doi.org/10.1038/s41598-017-15019-y.
Malabirade, Antoine, Javier Morgado-Brajones, Sylvain Trépout, Frank Wien, Ileana Marquez, Jérôme Seguin, Sergio Marco, Marisela Velez, and Arluison Véronique. 2017. “Membrane Association of the Bacterial Riboregulator Hfq and Functional Perspectives.” Scientific Reports 7 (1): 10724. https://doi.org/10.1038/s41598-017-11157-5.
Jacques, Isabelle B., Mireille Moutiez, Jerzy Witwinowski, Emmanuelle Darbon, Cécile Martel, Jérôme Seguin, Emmanuel Favry, et al. 2015. “Analysis of 51 Cyclodipeptide Synthases Reveals the Basis for Substrate Specificity.” Nature Chemical Biology 11 (9): 721–27. https://doi.org/10.1038/nchembio.1868.
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