Autophagy and antiviral immunity


Jeger-Madiot, Raphaël, Romain Vaineau, Maud Heredia, Nicolas Tchitchek, Lisa Bertrand, Mathias Pereira, Océane Konza, et al. 2022. “Naive and Memory CD4+ T Cell Subsets Can Contribute to the Generation of Human Tfh Cells.” IScience 25 (1).
Lesage, Sarah, Maxime Chazal, Guillaume Beauclair, Damien Batalie, Silvia Cerboni, Elodie Couderc, Aurianne Lescure, et al. 2021. “Discovery of Genes That Modulate Flavivirus Replication in an Interferon-Dependent Manner.” Journal of Molecular Biology, September, 167277.
Hernandez, Eva, Clémence Taisne, Marion Lussignol, Audrey Esclatine, and Marc Labetoulle. 2021. “Commercially Available Eye Drops Containing Trehalose Protect Against Dry Conditions via Autophagy Induction.” Journal of Ocular Pharmacology and Therapeutics: The Official Journal of the Association for Ocular Pharmacology and Therapeutics, July.
Bakoa, Florian, Christophe Préhaud, Guillaume Beauclair, Maxime Chazal, Nathalie Mantel, Monique Lafon, and Nolwenn Jouvenet. 2021. “Genomic Diversity Contributes to the Neuroinvasiveness of the Yellow Fever French Neurotropic Vaccine.” NPJ Vaccines 6 (1): 64.
Klionsky, Daniel J., Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. 2021. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition).” Autophagy, February, 1–382.
Mori, Luisa, Katharine Jenike, Yang-Hui Jimmy Yeh, Benoît Lacombe, Chuan Li, Adam J. Getzler, Sonia Mediouni, et al. 2021. “The XPB Subunit of the TFIIH Complex Plays a Critical Role in HIV-1 Transcription, and XPB Inhibition by Spironolactone Prevents HIV-1 Reactivation from Latency.” Journal of Virology 95 (4).



 Glon DLussignol M and Esclatine A (2020). La mitophagie : une stratégie du virus d’Epstein-Barr pour échapper à l’immunité innée. Médecine/Sciences 36 (11): 990–93.

 López Giuliani AC, Hernández E, Tohmé MJ, Taisne C, Roldán JS, García Samartino C, Lussignol M, Codogno P, María I. Colombo MI, Esclatine A* and Delgui LR* (2020). Human Cytomegalovirus Inhibits Autophagy of Renal Tubular Epithelial Cells and Promotes Cellular Enlargement. Frontiers in Cellular and Infection Microbiology 10: 474.

 Martella C, Tollenaere A.I, Waast L, Lacombe B, Groussaud D, Margottin-Goguet F, Ramírez BC and Pique C (2020). Human T-cell lymphotropic virus type 1 transactivator Tax exploits the XPB subunit of TFIIH during viral transcription. Journal of Virology 94:e02171-19.

 Vilmen GGlon D, Siracusano G, Lussignol M, Shao Z, Hernández E, Perdiz D, Quignon F, Mouna L, Poüs C, Gruffat H, Maréchal V and Esclatine A (2020). BHRF1, a BCL2 Viral Homolog, Disturbs Mitochondrial Dynamics and Stimulates Mitophagy to Dampen Type I IFN Induction. Autophagy 0 (0): 1–20.


 Beilstein F, Cohen GH, Eisenberg RJ, Nicolas V, Esclatine A and Pasdeloup D (2019). Dynamic Organization of Herpesvirus Glycoproteins on the Viral Envelope Revealed by Super-Resolution Microscopy. PLoS Pathogens 15 (12): e1008209.

 Moris APereira M and Chakrabarti L (2019). A Role for Antibodies in Natural HIV Control. Current Opinion in HIV and AIDS 14 (4): 265–72.

 Poccardi NRousseau A, Haigh O, Takissian J, Naas T, Deback C, Trouillaud L, Issa M, Roubille S, Juillard F, Efstathiou S, Lomonte P and Labetoulle M (2019). Herpes Simplex Virus 1 Replication, Ocular Disease, and Reactivations from Latency Are Restricted Unilaterally after Inoculation of Virus into the Li. Journal of Virology 93 (24): e01586-19.

 Schönfeld M, Knackmuss U, Chandorkar P, Hörtnagl P, Hope TJ, Moris A, Bellmann-Weiler R, Lass-Flörl C, Posch W and Wilflingseder D (2019). Co- but Not Sequential Infection of DCs Boosts Their HIV-Specific CTL-Stimulatory Capacity. Frontiers in Immunology 10: 1123.

 Taisne CLussignol MHernández EMoris AMouna L and Esclatine A (2019). Human Cytomegalovirus Hijacks the Autophagic Machinery and LC3 Homologs in Order to Optimize Cytoplasmic Envelopment of Mature Infectious Particles. Scientific Reports 9 (1): 4560.


 Bendenoun M, Samri A, Avettand-Fènoël V, Cardinaud S, Descours B, Carcelain G, Mazeron M-C, Bergmann J-F, Urrutia A, Moris A, Rouzioux C, Simon F, Andre P, Pocard M, Dray X, Mourez T, Vieillard V, Autran B, Barin F and Sellier P (2018). What Is the most Important for Elite Control: Genetic Background of Patient, Genetic Background of Partner, both or neither? Description of Complete Natural History within a Couple of MSM. EbioMedecine 27: 51-60

 Cohen C, Corpet A, Roubille S, Maroui MA, Poccardi NRousseau A, Kleijwegt C, Binda O, Texier P, Sawtell N, Labetoulle M and Lomonte P (2018). Promyelocytic Leukemia (PML) Nuclear Bodies (NBs) Induce Latent/Quiescent HSV-1 Genomes Chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis. PLoS Pathogens 14 (9): e1007313.

 Colomer-Lluch M, Ruiz A, Moris A and Prado JG (2018). Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1. Front Immunol 9:2876.


 Cardinaud S, Urrutia A, Rouers A, Coulon PG, Kervevan J, Richetta C, Bet A, Atangana Maze E, Larsen M, Iglesias MC, Appay V, Graff-Dubois S and Moris A (2017). Triggering of TLR-3, -4, NOD2 and DC-SIGN reduces viral replication and increases T-cell activation capacity of HIV-infected human dendritic cells. Euro J. Immunol 47(5):818-829.

 Lussignol M and Esclatine A (2017). Herpesvirus and Autophagy: “All Right, Everybody Be Cool, This Is a Robbery!” Viruses 9 (12): 372.

 Monel B, Compton AA, Bruel T, Amraoui S, Burlaud-Gaillard J, Roy N, Guivel-Benhassine F, Porrot F, Génin P, Meertens L, Sinigaglia L, Jouvenet N, Weil R, Casartelli N, Demangel C, Simon-Lorière E, Moris A, Roingeard P, Amara A and Schwartz O (2017). Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. EMBO J. 36:1653-1668.

 Rouers A, Jeger-Madiot R, Moris A and Graff-Dubois S (2017). Follicular helper T cells and HIV – United for better and worse. Médecine/Sciences 33(10):878-886.

 Rouers A, Klingler J, Su B, Samri A, Laumond G, Even S, Avettand-Fenoel V, Richetta C, Paul N, Boufassa F, Hocqueloux L, Mouquet H, Rouzioux C, Lambotte O, Autran B, Graff-Dubois S, Moog C and Moris A (2017). HIV-specific B cell frequency correlates with neutralization breadth in patients naturally controlling HIV-infection. EbioMedecine 21:158-169.

 Silvin A, Yu CI, Lahaye X, Imperatore F, Brault JP, Cardinaud S, Becker C, Kwan WH, Conrad C, Maurin M, Goudot C, Marques-Ladeira S, Wang Y, Pascual V, Anguiano E, Albrecht RA, Iannacone M, García-Sastre A, Goud B, Dalod M, Moris A, Merad M, Palucka AK and Manel N (2017). Constitutive resistance to viral infection in human CD141+ dendritic cells. Sci. Immunol. 2 (13):8071.

 Vergne I, Lafont F, Espert L, Esclatine A and Biard-Piechaczyk M. (2017). Autophagie, Protéines ATG et Maladies Infectieuses. Médecine/Sciences 33 (3): 312–18.

 Xu Y, Phetsouphanh C, Suzuki K, Aggarwal A, Graff-Dubois S, Roche M, Bailey M, Alcantara S, Flanagan S, Cash K, Siva R, Koelsch KK, Autran B, Harvey R, Gorry PR, Moris A, Cooper DA, Turville S, Kent SJ, Kelleher and Zaunders J (2017). HIV-1 and SIV predominantly use CCR5 expressed on a precursor population to establish infection in T follicular helper cells. Frontiers in Immunol 8:376.


 Caucheteux SM, Mitchell JP, Ivory MO, Hirosue S, Hakobyan S, Dolton G, Ladell K, Price D, Sewell A, Nestle F, Moris A, Karoo RO, Birchall JC, Hubbel JA, Blanchet FP and Piguet V (2016). A Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1. J Invest Dermatol. 136 (6):1172-81.

 Coulon PG, Richetta C, Rouers A, Blanchet FP, Urrutia U, Guerbois M, Piguet V, Theodorou I, Bet A, Schwartz O, Tangy F, Graff-Dubois S, Cardinaud S and Moris A (2016). HIV-infected dendritic cells present endogenous MHC-II-restricted antigens to HIV-specific CD4 + T cells. J. Immunol. 197(2):517-32.

 Graff-Dubois S, Rouers A and Moris A (2016). Impact of chronic HIV/SIV infection on germinal center reaction: lessons from analysis of T follicular cell subsets. Frontiers in Immunology 7:501.

 Hamimi, C, David A, Versmisse P, Weiss L, Bruel T, Zucman D, Appay V, Moris A, Ungeheuer MN, Lascoux-Combe C, Barre-Sinoussi F, Muller-Trutwin M, Boufassa F, Lambotte O, Pancino G, Saez-Cirion A, and ACC cohort (2016). Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles. PLoS One 11: e0160251.

 Jimenez E, Ruiz A, Kloverpris HN, Rodriguez-Plata MT, Pena R, Blondeau C, Selwood DL, Izquierdo-Useros N, Moris A, Clotet B, Goulder P, Towers GJ and Prado LG (2016). Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cells. J Virol 90 (19): 8552-8562.

 Klionsky DJ et al., (2462 authors, including Moris A) (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12(1):1-222. .

 Maroui MA, Callé A, Cohen C, Streichenberger N, Texier P, Takissian JRousseau A Poccardi N, Welsch J, Corpet A, Schaeffer L, Labetoulle M and Lomonte P (2016). Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment. PLoS Pathogens 12 (9): e1005834.

 Mouna LHernandez E, Bonte D, Brost R, Amazit L, Delgui LR, Brune W, Geballe AP, Beau I and Esclatine A (2016). Analysis of the Role of Autophagy Inhibition by Two Complementary Human Cytomegalovirus BECN1/Beclin 1-Binding Proteins. Autophagy 12 (2): 327–42.

 Sicard A, Koenig A, Graff-Dubois S, Dussurgey S, Rouers A, Dubois V, Blanc P, Chartoire D, Errazuriz-Cerda E, Paidassi H, Taillardet M, Morelon E, Moris A, Defrance T and Thaunat O (2016). B Cells Loaded with Synthetic Particulate Antigens: A Versatile Platform to Generate Antigen-Specific Helper T Cells for Cell Therapy. Nano Lett. 16(1):297-308.

 Siracusano G, Venuti A, Lombardo D, Mastino A, Esclatine A and Sciortino MT (2016). Early Activation of MyD88-Mediated Autophagy Sustains HSV-1 Replication in Human Monocytic THP-1 Cells. Scientific Reports 6: 31302.

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