Senescence and Genome Stability

Publications

Tewary, Gargi, Benjamin Freyter, Mutaz Abd Al-Razaq, Hendrik Auerbach, Matthias W. Laschke, Tanja Kübelbeck, Antonia Kolb, et al. 2023. “Immunomodulatory Effects of Histone Variant H2A.J in Ionizing Radiation Dermatitis.” International Journal of Radiation Oncology, Biology, Physics, September, S0360-3016(23)07934-8. https://doi.org/10.1016/j.ijrobp.2023.09.022.
Vaitinadapoulé, Hanielle, Sylvain Poinard, Zhiguo He, Alina Pascale-Hamri, Justin Thomas, Philippe Gain, Jean-Yves Thuret, Frédéric Mascarelli, Gilles Thuret, and French Fuchs Study Group (FFSG). 2023. “Nanotopography by Chromatic Confocal Microscopy of the Endothelium in Fuchs Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy and Healthy Corneas.” The British Journal of Ophthalmology, September, bjo-2023-323297. https://doi.org/10.1136/bjo-2023-323297.
Abd Al-Razaq, Mutaz A., Benjamin M. Freyter, Anna Isermann, Gargi Tewary, Adèle Mangelinck, Carl Mann, and Claudia E. Rübe. 2023. “Role of Histone Variant H2A.J in Fine-Tuning Chromatin Organization for the Establishment of Ionizing Radiation-Induced Senescence.” Cells 12 (6): 916. https://doi.org/10.3390/cells12060916.
L’Hôte, Valentin, Carl Mann, and Jean-Yves Thuret. 2022. “From the Divergence of Senescent Cell Fates to Mechanisms and Selectivity of Senolytic Drugs.” Open Biology 12 (9): 220171. https://doi.org/10.1098/rsob.220171.
Redon, Christophe E., Zoe Schmal, Gargi Tewary, Adèle Mangelinck, Régis Courbeyrette, Jean-Yves Thuret, Mirit I. Aladjem, William M. Bonner, Claudia E. Rübe, and Carl Mann. 2021. “Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells.” Genes 12 (11): 1665. https://doi.org/10.3390/genes12111665.
L’Hôte, Valentin, Régis Courbeyrette, Guillaume Pinna, Jean-Christophe Cintrat, Gwenaëlle Le Pavec, Agnès Delaunay-Moisan, Carl Mann, and Jean-Yves Thuret. 2021. “Ouabain and Chloroquine Trigger Senolysis of BRAF-V600E-Induced Senescent Cells by Targeting Autophagy.” Aging Cell, August, e13447. https://doi.org/10.1111/acel.13447.
Mullani, Nowsheen, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickael Costallat, Eric Batsché, Michele Goodhardt, Giovanni Cenci, Carl Mann, and Christian Muchardt. 2021. “Reduced RNA Turnover as a Driver of Cellular Senescence.” Life Science Alliance 4 (3). https://doi.org/10.26508/lsa.202000809.
Mangelinck, Adèle, and Carl Mann. 2021. “DNA Methylation and Histone Variants in Aging and Cancer.” International Review of Cell and Molecular Biology 364:1–110. https://doi.org/10.1016/bs.ircmb.2021.06.002.
Isermann, Anna, Carl Mann, and Claudia E. Rübe. 2020. “Histone Variant H2A.J Marks Persistent DNA Damage and Triggers the Secretory Phenotype in Radiation-Induced Senescence.” International Journal of Molecular Sciences 21 (23): 9130. https://doi.org/10.3390/ijms21239130.
Nguyen, Hoang Quy, Yazid Belkacemi, Carl Mann, Françoise Hoffschir, Stéphane Kerbrat, Mathieu Surenaud, Patricia Zadigue, Alexandre de La Taille, Paul-Henri Romeo, and Sabine Le Gouvello. 2020. “Human CCR6+ Th17 Lymphocytes Are Highly Sensitive to Radiation-Induced Senescence and Are a Potential Target for Prevention of Radiation-Induced Toxicity.” International Journal of Radiation Oncology, Biology, Physics 108 (1): 314–25. https://doi.org/10.1016/j.ijrobp.2019.10.045.
Armengaud, Jean, Agnès Delaunay‐Moisan, Jean-Yves Thuret, Eelco van Anken, Diego Acosta‐Alvear, Tomás Aragón, Carolina Arias, et al. 2020. “The Importance of Naturally Attenuated SARS-CoV-2in the Fight against COVID-19.” Environmental Microbiology 22 (6): 1997–2000. https://doi.org/10.1111/1462-2920.15039.
Bakail, May, Albane Gaubert, Jessica Andreani, Gwenaëlle Moal, Guillaume Pinna, Ekaterina Boyarchuk, Marie-Cécile Gaillard, et al. 2019. “Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.” Cell Chemical Biology 26 (11): 1573-1585.e10. https://doi.org/10.1016/j.chembiol.2019.09.002.
Carvalho, Cyril, Valentin L’Hôte, Régis Courbeyrette, Gueorgui Kratassiouk, Guillaume Pinna, Jean-Christophe Cintrat, Cyril Denby-Wilkes, et al. 2019. “Glucocorticoids Delay RAF-Induced Senescence Promoted by EGR1.” Journal of Cell Science 132 (16): jcs230748. https://doi.org/10.1242/jcs.230748.
Contrepois, Kévin, Clément Coudereau, Bérénice A. Benayoun, Nadine Schuler, Pierre-François Roux, Oliver Bischof, Régis Courbeyrette, et al. 2017. “Histone Variant H2A.J Accumulates in Senescent Cells and Promotes Inflammatory Gene Expression.” Nature Communications 8 (May):14995. https://doi.org/10.1038/ncomms14995.
Culerrier, Raphaël, Maëlle Carraz, Carl Mann, and Malek Djabali. 2016. “MSK1 Triggers the Expression of the INK4AB/ARF Locus in Oncogene-Induced Senescence.” Molecular Biology of the Cell 27 (17): 2726–34. https://doi.org/10.1091/mbc.E15-11-0772.
Hamdi, Dounia Houria, François Chevalier, Jean-Emmanuel Groetz, Florent Durantel, Jean-Yves Thuret, Carl Mann, and Yannick Saintigny. 2016. “Comparable Senescence Induction in Three-Dimensional Human Cartilage Model by Exposure to Therapeutic Doses of X-Rays or C-Ions.” International Journal of Radiation Oncology, Biology, Physics 95 (1): 139–46. https://doi.org/10.1016/j.ijrobp.2016.02.014.
Lazorthes, Sandra, Céline Vallot, Sébastien Briois, Marion Aguirrebengoa, Jean-Yves Thuret, Georges St Laurent, Claire Rougeulle, et al. 2015. “Erratum: A VlincRNA Participates in Senescence Maintenance by Relieving H2AZ-Mediated Repression at the INK4 Locus.” Nature Communications 6 (April):6918. https://doi.org/10.1038/ncomms7918.
Chandra, Tamir, Philip Andrew Ewels, Stefan Schoenfelder, Mayra Furlan-Magaril, Steven William Wingett, Kristina Kirschner, Jean-Yves Thuret, Simon Andrews, Peter Fraser, and Wolf Reik. 2015. “Global Reorganization of the Nuclear Landscape in Senescent Cells.” Cell Reports 10 (4): 471–83. https://doi.org/10.1016/j.celrep.2014.12.055.
Lazorthes, Sandra, Céline Vallot, Sébastien Briois, Marion Aguirrebengoa, Jean-Yves Thuret, Georges St Laurent, Claire Rougeulle, et al. 2015. “A VlincRNA Participates in Senescence Maintenance by Relieving H2AZ-Mediated Repression at the INK4 Locus.” Nature Communications 6 (January):5971. https://doi.org/10.1038/ncomms6971.
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