Senescence and Genome Stability

Publications

L’Hôte, Valentin, Régis Courbeyrette, Guillaume Pinna, Jean-Christophe Cintrat, Gwenaëlle Le Pavec, Agnès Delaunay-Moisan, Carl Mann, and Jean-Yves Thuret. 2021. “Ouabain and Chloroquine Trigger Senolysis of BRAF-V600E-Induced Senescent Cells by Targeting Autophagy.” Aging Cell, August, e13447. https://doi.org/10.1111/acel.13447.
Mullani, Nowsheen, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickael Costallat, Eric Batsché, Michele Goodhardt, Giovanni Cenci, Carl Mann, and Christian Muchardt. 2021. “Reduced RNA Turnover as a Driver of Cellular Senescence.” Life Science Alliance 4 (3). https://doi.org/10.26508/lsa.202000809.
Isermann, Anna, Carl Mann, and Claudia E. Rübe. 2020. “Histone Variant H2A.J Marks Persistent DNA Damage and Triggers the Secretory Phenotype in Radiation-Induced Senescence.” International Journal of Molecular Sciences 21 (23): 9130. https://doi.org/10.3390/ijms21239130.
Nguyen, Hoang Quy, Yazid Belkacemi, Carl Mann, Françoise Hoffschir, Stéphane Kerbrat, Mathieu Surenaud, Patricia Zadigue, Alexandre de La Taille, Paul-Henri Romeo, and Sabine Le Gouvello. 2020. “Human CCR6+ Th17 Lymphocytes Are Highly Sensitive to Radiation-Induced Senescence and Are a Potential Target for Prevention of Radiation-Induced Toxicity.” International Journal of Radiation Oncology, Biology, Physics 108 (1): 314–25. https://doi.org/10.1016/j.ijrobp.2019.10.045.
Armengaud, Jean, Agnès Delaunay‐Moisan, Jean-Yves Thuret, Eelco van Anken, Diego Acosta‐Alvear, Tomás Aragón, Carolina Arias, et al. 2020. “The Importance of Naturally Attenuated SARS-CoV-2in the Fight against COVID-19.” Environmental Microbiology 22 (6): 1997–2000. https://doi.org/10.1111/1462-2920.15039.
Bakail, May, Albane Gaubert, Jessica Andreani, Gwenaëlle Moal, Guillaume Pinna, Ekaterina Boyarchuk, Marie-Cécile Gaillard, et al. 2019. “Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1.” Cell Chemical Biology 26 (11): 1573-1585.e10. https://doi.org/10.1016/j.chembiol.2019.09.002.
Carvalho, Cyril, Valentin L’Hôte, Régis Courbeyrette, Gueorgui Kratassiouk, Guillaume Pinna, Jean-Christophe Cintrat, Cyril Denby-Wilkes, et al. 2019. “Glucocorticoids Delay RAF-Induced Senescence Promoted by EGR1.” Journal of Cell Science 132 (16): jcs230748. https://doi.org/10.1242/jcs.230748.
Contrepois, Kévin, Clément Coudereau, Bérénice A. Benayoun, Nadine Schuler, Pierre-François Roux, Oliver Bischof, Régis Courbeyrette, et al. 2017. “Histone Variant H2A.J Accumulates in Senescent Cells and Promotes Inflammatory Gene Expression.” Nature Communications 8 (May): 14995. https://doi.org/10.1038/ncomms14995.
Culerrier, Raphaël, Maëlle Carraz, Carl Mann, and Malek Djabali. 2016. “MSK1 Triggers the Expression of the INK4AB/ARF Locus in Oncogene-Induced Senescence.” Molecular Biology of the Cell 27 (17): 2726–34. https://doi.org/10.1091/mbc.E15-11-0772.
Hamdi, Dounia Houria, François Chevalier, Jean-Emmanuel Groetz, Florent Durantel, Jean-Yves Thuret, Carl Mann, and Yannick Saintigny. 2016. “Comparable Senescence Induction in Three-Dimensional Human Cartilage Model by Exposure to Therapeutic Doses of X-Rays or C-Ions.” International Journal of Radiation Oncology, Biology, Physics 95 (1): 139–46. https://doi.org/10.1016/j.ijrobp.2016.02.014.
Lazorthes, Sandra, Céline Vallot, Sébastien Briois, Marion Aguirrebengoa, Jean-Yves Thuret, Georges St Laurent, Claire Rougeulle, et al. 2015. “Erratum: A VlincRNA Participates in Senescence Maintenance by Relieving H2AZ-Mediated Repression at the INK4 Locus.” Nature Communications 6 (April): 6918. https://doi.org/10.1038/ncomms7918.
Chandra, Tamir, Philip Andrew Ewels, Stefan Schoenfelder, Mayra Furlan-Magaril, Steven William Wingett, Kristina Kirschner, Jean-Yves Thuret, Simon Andrews, Peter Fraser, and Wolf Reik. 2015. “Global Reorganization of the Nuclear Landscape in Senescent Cells.” Cell Reports 10 (4): 471–83. https://doi.org/10.1016/j.celrep.2014.12.055.
Lazorthes, Sandra, Céline Vallot, Sébastien Briois, Marion Aguirrebengoa, Jean-Yves Thuret, Georges St Laurent, Claire Rougeulle, et al. 2015. “A VlincRNA Participates in Senescence Maintenance by Relieving H2AZ-Mediated Repression at the INK4 Locus.” Nature Communications 6 (January): 5971. https://doi.org/10.1038/ncomms6971.
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