CryoEM
Cryo-electron microscopy

Publications

Royet, Adrien, Rémi Ruedas, Laetitia Gargowitsch, Virginie Gervais, Johann Habersetzer, Laura Pieri, Malika Ouldali, et al. 2024. “Nonstructural Protein 4 of Human Norovirus Self-Assembles into Various Membrane-Bridging Multimers.” The Journal of Biological Chemistry, August, 107724. https://doi.org/10.1016/j.jbc.2024.107724.
Glon, Damien, Benjamin Léonardon, Ariane Guillemot, Aurélie Albertini, Cécile Lagaudrière-Gesbert, and Yves Gaudin. 2024. “Biomolecular Condensates with Liquid Properties Formed during Viral Infections.” Microbes and Infection, August, 105402. https://doi.org/10.1016/j.micinf.2024.105402.
Mance, Lucija, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, Siham Zentout, Marin Biliškov, et al. 2024. “Dynamic BTB-Domain Filaments Promote Clustering of ZBTB Proteins.” Molecular Cell 84 (13): 2490-2510.e9. https://doi.org/10.1016/j.molcel.2024.05.029.
Jaffal, Hoda, Mounia Kortebi, Pauline Misson, Paulo Tavares, Malika Ouldali, Hervé Leh, Sylvie Lautru, Virginia S. Lioy, François Lecointe, and Stéphanie G. Bury-Moné. 2024. “Prophage Induction Can Facilitate the in Vitro Dispersal of Multicellular Streptomyces Structures.” PLoS Biology 22 (7): e3002725. https://doi.org/10.1371/journal.pbio.3002725.
Auzat, Isabelle, Malika Ouldali, Eric Jacquet, Beatrix Fauler, Thorsten Mielke, and Paulo Tavares. 2024. “Dual Function of a Highly Conserved Bacteriophage Tail Completion Protein Essential for Bacteriophage Infectivity.” Communications Biology 7 (1): 1–12. https://doi.org/10.1038/s42003-024-06221-6.
Ruedas, Rémi, Rémi Vuillemot, Thibault Tubiana, Jean-Marie Winter, Laura Pieri, Ana-Andreea Arteni, Camille Samson, Slavica Jonic, Magali Mathieu, and Stéphane Bressanelli. 2024. “Structure and Conformational Variability of the HER2-Trastuzumab-Pertuzumab Complex.” Journal of Structural Biology 216 (2): 108095. https://doi.org/10.1016/j.jsb.2024.108095.
Babot, Marion, Yves Boulard, Samira Agouda, Laura Pieri, Sonia Fieulaine, Stéphane Bressanelli, and Virginie Gervais. 2024. “Oligomeric Assembly of the C-Terminal and Transmembrane Region of SARS-CoV-2 Nsp3.” Journal of Virology, March, e0157523. https://doi.org/10.1128/jvi.01575-23.
Rossier, Ombeline, Cécile Labarre, Anne Lopes, Monique Auberdiac, Kevin Tambosco, Daniel Delaruelle, Hakima Abes, et al. 2024. “Genome Sequence of PSonyx, a Singleton Bacteriophage Infecting Corynebacterium Glutamicum.” Microbiology Resource Announcements, January, e0115523. https://doi.org/10.1128/mra.01155-23.
Jaffal, Hoda, Mounia Kortebi, Pauline Misson, Paulo Tavares, Malika Ouldali, Hervé Leh, Sylvie Lautru, Virginia S. Lioy, François Lecointe, and Stéphanie Bury-Moné. 2024. “Characterization of a Novel Temperate Phage Facilitating in Vitro Dispersal of Multicellular Bacteria.” bioRxiv. https://doi.org/10.1101/2023.07.22.549817.
Jaudoin, Céline, Maria Maue Gehrke, Isabelle Grillo, Fabrice Cousin, Malika Ouldali, Ana-Andreea Arteni, Evelyne Ferrary, et al. 2023. “Release of Liposomes from Hyaluronic Acid-Based Hybrid Systems: Effects of Liposome Surface and Size.” International Journal of Pharmaceutics 648 (December):123560. https://doi.org/10.1016/j.ijpharm.2023.123560.
Ghouil, Rania, Simona Miron, Koichi Sato, Dejan Ristic, Sari E. van Rossum-Fikkert, Pierre Legrand, Malika Ouldali, et al. 2023. “BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination.” Science Advances 9 (43): eadi7352. https://doi.org/10.1126/sciadv.adi7352.
Miller, Jessalyn, Agathe Urvoas, Benoit Gigant, Malika Ouldali, Ana Arteni, Agnes Mesneau, Marie Valerio-Lepiniec, Franck Artzner, Erik Dujardin, and Philippe Minard. 2023. “Engineering of Brick and Staple Components for Ordered Assembly of Synthetic Repeat Proteins.” Journal of Structural Biology 215 (3): 108012. https://doi.org/10.1016/j.jsb.2023.108012.
Veremeienko, Vasyl, Chloe Magne, Minh-Huong Ha-Thi, Ana Arteni, Andrew Pascal, Mikas Vengris, Thomas Pino, Robert Bruno, and Manuel Llansola-Portoles. 2023. “Singlet Fission in Heterogeneous Lycopene Aggregates.” ChemRxiv. https://doi.org/10.26434/chemrxiv-2023-t3q2s.
Pourcel, Christine, Malika Ouldali, Paulo Tavares, and Christiane Essoh. 2023. “The Saclayvirus Aci01-1 Very Long and Complex Fiber and Its Receptor at the Acinetobacter Baumannii Surface.” Archives of Virology 168 (7): 187. https://doi.org/10.1007/s00705-023-05817-3.
Honfozo, Ariane, Rania Ghouil, Tchilabalo Dilezitoko Alayi, Malika Ouldali, Ana-Andreea Arteni, Cynthia Menonve Atindehou, Lucie Ayi Fanou, Yetrib Hathout, Sophie Zinn-Justin, and Stanislas Tomavo. 2023. “The Luminal Domain of Toxoplasma Gondii Sortilin Adopts a Ring-Shaped Structure Exhibiting Motifs Specific to Apicomplexan Parasites.” Frontiers in Parasitology 2. https://www.frontiersin.org/articles/10.3389/fpara.2023.1103772.
Jaudoin, Céline, Isabelle Grillo, Fabrice Cousin, Maria Gehrke, Malika Ouldali, Ana-Andreea Arteni, Luc Picton, et al. 2022. “Hybrid Systems Combining Liposomes and Entangled Hyaluronic Acid Chains: Influence of Liposome Surface and Drug Encapsulation on the Microstructure.” Journal of Colloid and Interface Science 628 (December):995–1007. https://doi.org/10.1016/j.jcis.2022.07.146.
Bousset, Luc, Ania Alik, Ana Arteni, Anja Böckmann, Beat H. Meier, and Ronald Melki. 2022. “α-Synuclein Fibril, Ribbon and Fibril-91 Amyloid Polymorphs Generation for Structural Studies.” In Protein Aggregation: Methods and Protocols, edited by Andrzej Stanisław Cieplak, 345–55. Methods in Molecular Biology. New York, NY: Springer US. https://doi.org/10.1007/978-1-0716-2597-2_23.
Cargemel, Claire, Hélène Walbott, Dominique Durand, Pierre Legrand, Malika Ouldali, Jean-Luc Ferat, Stéphanie Marsin, and Sophie Quevillon-Cheruel. 2022. “The Apo-Form of the Vibrio Cholerae Replicative Helicase DnaB Is a Labile and Inactive Planar Trimer of Dimers.” FEBS Letters n/a (n/a). https://doi.org/10.1002/1873-3468.14403.
Pieri, Laura, Fengbin Wang, Ana-Andreea Arteni, Matthijn Vos, Jean-Marie Winter, Marie-Hélène Le Du, Franck Artzner, et al. 2022. “Atomic Structure of Lanreotide Nanotubes Revealed by Cryo-EM.” Proceedings of the National Academy of Sciences 119 (4). https://doi.org/10.1073/pnas.2120346119.
Romero Castro, Valeria Lizeth, Brahim Nomeir, Ana Andreea Arteni, Malika Ouldali, Jean-Luc Six, and Khalid Ferji. 2021. “Dextran-Coated Latex Nanoparticles via Photo-RAFT Mediated Polymerization Induced Self-Assembly.” Polymers 13 (23): 4064. https://doi.org/10.3390/polym13234064.
Ghouil, Rania, Simona Miron, Lieke Koornneef, Jasper Veerman, Maarten W. Paul, Marie-Hélène Le Du, Esther Sleddens-Linkels, et al. 2021. “BRCA2 Binding through a Cryptic Repeated Motif to HSF2BP Oligomers Does Not Impact Meiotic Recombination.” Nature Communications 12 (1): 4605. https://doi.org/10.1038/s41467-021-24871-6.
Ikkene, Djallal, Ana Andreea Arteni, Malika Ouldali, Gregory Francius, Annie Brûlet, Jean-Luc Six, and Khalid Ferji. 2021. “Direct Access to Polysaccharide-Based Vesicles with a Tunable Membrane Thickness in a Large Concentration Window via Polymerization-Induced Self-Assembly.” Biomacromolecules 22 (7): 3128–37. https://doi.org/10.1021/acs.biomac.1c00569.
Ould Ali, Malika, Karine Moncoq, Agnès de la Croix de la Valette, Ana A. Arteni, Jean-Michel Betton, and Jean Lepault. 2021. “Study of Membrane Deformations Induced by Hepatitis C Protein NS4B and Its Terminal Amphipathic Peptides.” Biochimica et Biophysica Acta (BBA) - Biomembranes 1863 (3): 183537. https://doi.org/10.1016/j.bbamem.2020.183537.
Fieulaine, Sonia, Martin D. Witte, Christopher S. Theile, Maya Ayach, Hidde L. Ploegh, Isabelle Jupin, and Stéphane Bressanelli. 2020. “Turnip Yellow Mosaic Virus Protease Binds Ubiquitin Suboptimally to Fine-Tune Its Deubiquitinase Activity.” Journal of Biological Chemistry 295 (40): 13769–83. https://doi.org/10.1074/jbc.RA120.014628.
Beilstein, Frauke, Abbas Abou Hamdan, Hélène Raux, Laura Belot, Malika Ouldali, Aurélie A. Albertini, and Yves Gaudin. 2020. “Identification of a PH-Sensitive Switch in VSV-G and a Crystal Structure of the G Pre-Fusion State Highlight the VSV-G Structural Transition Pathway.” Cell Reports 32 (7): 108042. https://doi.org/10.1016/j.celrep.2020.108042.
Ikkene, D., A. A. Arteni, H. Song, H. Laroui, J-L. Six, and K. Ferji. 2020. “Synthesis of Dextran-Based Chain Transfer Agent for RAFT-Mediated Polymerization and Glyco-Nanoobjects Formulation.” Carbohydrate Polymers 234 (April):115943. https://doi.org/10.1016/j.carbpol.2020.115943.
Belot, Laura, Malika Ouldali, Stéphane Roche, Pierre Legrand, Yves Gaudin, and Aurélie A. Albertini. 2020. “Crystal Structure of Mokola Virus Glycoprotein in Its Post-Fusion Conformation.” PLoS Pathogens 16 (3): e1008383. https://doi.org/10.1371/journal.ppat.1008383.
Guerrero-Ferreira, Ricardo, Nicholas M. I. Taylor, Ana-Andreea Arteni, Pratibha Kumari, Daniel Mona, Philippe Ringler, Markus Britschgi, et al. 2019. “Two New Polymorphic Structures of Human Full-Length Alpha-Synuclein Fibrils Solved by Cryo-Electron Microscopy.” Elife 8 (December):e48907. https://doi.org/10.7554/eLife.48907.
Essawy, Nada, Camille Samson, Ambre Petitalot, Sophie Moog, Anne Bigot, Isaline Herrada, Agathe Marcelot, Ana-Andreea Arteni, Catherine Coirault, and Sophie Zinn-Justin. 2019. “An Emerin LEM-Domain Mutation Impairs Cell Response to Mechanical Stress.” Cells 8 (6): 570. https://doi.org/10.3390/cells8060570.
Guerrero-Ferreira, Ricardo, Nicholas M. I. Taylor, Ana-Andrea Arteni, Pratibha Kumari, Daniel Mona, Philippe Ringler, Markus Britschgi, et al. 2019. “Two New Polymorphic Structures of Alpha-Synuclein Solved by Cryo-Electron Microscopy.” BioRxiv, May, 654582. https://doi.org/10.1101/654582.
Campanacci, Valérie, Agathe Urvoas, Soraya Cantos-Fernandes, Magali Aumont-Nicaise, Ana-Andreea Arteni, Christophe Velours, Marie Valerio-Lepiniec, et al. 2019. “Insight into Microtubule Nucleation from Tubulin-Capping Proteins.” Proceedings of the National Academy of Sciences of the United States of America 116 (20): 9859–64. https://doi.org/10.1073/pnas.1813559116.
Samson, Camille, Ambre Petitalot, Florian Celli, Isaline Herrada, Virginie Ropars, Marie-Helene Le Du, Naima Nhiri, et al. 2018. “Structural Analysis of the Ternary Complex between Lamin A/C, BAF and Emerin Identifies an Interface Disrupted in Autosomal Recessive Progeroid Diseases.” Nucleic Acids Research 46 (19): 10460–73. https://doi.org/10.1093/nar/gky736.
Ouldali, Malika, Virginie Maury, Gisèle Nicolas, and Jean Lepault. 2018. “Photosome Membranes Merge and Organize Tending towards Rhombohedral Symmetry When Light Is Emitted.” Journal of Structural Biology 202 (1): 35–41. https://doi.org/10.1016/j.jsb.2017.12.001.
Ma, Miao, Ines Li de La Sierra Gallay, Noureddine Lazar, Olivier Pellegrini, Jean Lepault, Ciarán Condon, Dominique Durand, and Herman van Tilbeurgh. 2017. “Trz1, the Long Form RNase Z from Yeast, Forms a Stable Heterohexamer with Endonuclease Nuc1 and Mutarotase.” The Biochemical Journal 474 (21): 3599–3613. https://doi.org/10.1042/BCJ20170435.
Baquero, Eduard, Aurélie A Albertini, Hélène Raux, Abbas Abou‐Hamdan, Elisabetta Boeri‐Erba, Malika Ouldali, Linda Buonocore, et al. 2017. “Structural Intermediates in the Fusion‐associated Transition of Vesiculovirus Glycoprotein.” The EMBO Journal 36 (5): 679–92. https://doi.org/10.15252/embj.201694565.
Samson, Camille, Florian Celli, Kitty Hendriks, Maximilian Zinke, Nada Essawy, Isaline Herrada, Ana-Andreea Arteni, et al. 2017. “Emerin Self-Assembly Mechanism: Role of the LEM Domain.” The FEBS Journal 284 (2): 338–52. https://doi.org/10.1111/febs.13983.

2020

  1. Malika Ouldali1, Karine Moncoq, Agnès de la Croix de la Valette, Ana A. Arteni, Jean Michel Betton and Jean Lepault, Visualization of the membrane deformations induced by Hepatitis C protein NS4B and its terminal amphipathic peptides, BBA, https://doi.org/10.1016/j.bbamem.2020.183537, December 2020
  2. Frauke Beilstein, Abbas Abou Hamdan, Hélène Raux, Laura Belot, Malika Ouldali, Aurélie A Albertini, Yves Gaudin, Identification of a pH-Sensitive Switch in VSV-G and a Crystal Structure of the G Pre-fusion State Highlight the VSV-G Structural Transition Pathway, Cell Rep., doi: 10.1016/j.celrep.2020.108042, August, 2020
  3. Djallal Ikkene, Ana Andreea Arteni, Malika Ouldali, Jean-Luc Six and Khalid Ferji, Self-assembly of amphiphilic copolymers containing polysaccharide: PISA versus nanoprecipitation, and the temperature effect, Polymer Chemistry, https://doi.org/10.1039/D0PY00407C, June, 2020
  4. Ikkene, AA. Arteni, H. Song, H. Laroui, J-L. Six, K. Ferji, Synthesis of Dextran-Based Chain Transfer Agent for RAFT-Mediated Polymerization and Glyco-Nanoobjects Formulation, Carbohydrate Polymers, https://doi.org/10.1016/j.carbpol.2020.115943, April, 2020
  5. Belot L, Ouldali M, Roche S, Legrand P, Gaudin Y, Albertini AA., Crystal structure of Mokola virus glycoprotein in its post-fusion conformation, PLoS Pathogen, doi: 10.1371/journal.ppat.1008383, Mars, 2020

2019

Scroll to Top