Intracellular Trafficking and Organelle Biogenesis
in Toxoplasma


Houngue, Rodrigue, Lamba Omar Sangaré, Tchilabalo Dilezitoko Alayi, Aissatou Dieng, Tristan Bitard-Feildel, Claire Boulogne, Christian Slomianny, et al. 2023. “Toxoplasma Membrane Inositol Phospholipid Binding Protein TgREMIND Is Essential for Secretory Organelle Function and Host Infection.” Cell Reports 43 (1): 113601.
Honfozo, Ariane, Rodrigue Houngue, Alexandre Vandeputte, Sébastien Dechavanne, Odilon Nouatin, Ménonvè Cynthia Atindehou, Lucie Ayi Fanou, et al. 2023. “An Image-Based High-Content Screening for Compounds Targeting Toxoplasma Gondii Repurposed Inhibitors Effective against the Malaria Parasite Plasmodium Falciparum.” Frontiers in Cellular and Infection Microbiology 13: 1102551.
Leleu, Inès, Delphine Genete, Sophie Salomé Desnoulez, Nasreddine Saidi, Priscille Brodin, Frank Lafont, Stanislas Tomavo, and Sylviane Pied. 2021. “A Noncanonical Autophagy Is Involved in the Transfer of Plasmodium-Microvesicles to Astrocytes.” Autophagy, November, 1–16.
Deffieu, Maika S., Tchilabalo Dilezitoko Alayi, Christian Slomianny, and Stanislas Tomavo. 2019. “The Toxoplasma Gondii Dense Granule Protein TgGRA3 Interacts with Host Golgi and Dysregulates Anterograde Transport.” Biology Open 8 (3): UNSP bio039818.

2012 to 2017

 – Draheim M, Wlodarczyk MF, Crozat K, Saliou JM, Alayi TD, Tomavo S, Hassan A, Salvioni A, Demarta-Gatsi C, Sidney J, Sette A, Dalod M, Berry A, Silvie O, Blanchard N. (2017) Profiling MHC II immunopeptidome of blood-stage malaria reveals that cDC1 control the functionality of parasite-specific CD4 T cells. EMBO Molecular Medicine 9: 1605-1621.

– Queval CJ, Song OR, Carralot JP, Saliou JM, Bongiovanni A, Deloison G, Deboosère N, Jouny S, Iantomasi R, Delorme V, Debrie AS, Park SJ, Gouveia JC, Tomavo S, Brosch R, Yoshimura A, Yeramian E & Brodin P.  (2017) Mycobacterium tuberculosis controls phagosome acidification by targeting CISH-mediated signaling. Cell Reports 20(13):3188-3198.

– Sakura T, Sindikubwabo F, Slomianny C, Oesterlin LK, Bousquet H, Langsley G, Hakimi MA, & Tomavo S. (2016) A critical role of Toxoplasma gondii vacuolar protein sorting VPS9 in secretory organelle biogenesis and host infection. Scientific Reports 6: 38842.

– Sangaré LO, Alayi TD, Hovasse A, Westermann B, Sindikubwabo F, Callebaut I, Werkmeister E, Lafont F, Slomianny C, Hakimi MA, Van Dorsselaer A, Schaeffer-Reiss C & Tomavo S (2016) Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection. Nature Communications 7:10191 doi: 10.1038/ncomms11191.

– Tomavo S (2015) Too much sugar puts a parasite in jeopardy. Cell Host Microbe 18: 641-643. 

– Sloves PJ, Mouveaux T, Ait-Yahia S, Vorng H, Everaere L, Sangare LO, Tsicopoulos A & Tomavo S (2015) Apical organelle secretion by Toxoplasma controls innate and adaptive immunity and mediates long-term protection. Journal of Infectious Diseases 212: 1449-1458.

– Tomavo S (2014) Evolutionarily repurposing of endosomal systems for apical organelle biogenesis in Toxoplasma gondii. International Journal for Parasitology 44: 133-138.

– Tomavo S, Slomianny C, Meissner M & Carruthers VB. (2013) Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion. PLoS Pathogens 9: e1003629.

– Sloves PJ, Delhaye S, Mouveaux T, Werkmeister E, Slomianny C, Hovasse A, Alayi TD, Callebaut I, Gaji RY, Schaeffer-Reiss C, Van Dorsselear A, Carruthers VB & Tomavo S (2012) Toxoplasma sortilin-like receptor regulates protein transport and is essential for apical secretory organelle biogenesis and host infection. Cell Host Microbe 11: 515-527.


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