The I2BC facilities are integrated into 5 National Infrastructures in Biology and Health (FRISBI, France Génomique, ProFI, France-BioImaging and Institut Français de Bioinformatique) and most of them are recognized at national level by the IBiSA label. The 500 annual users of the facilities have access to state-of-the-art technologies and methodologies. The facilities perform research and development, in collaboration with other national centers and with I2BC teams. Finally, the facilities are committed to training: each year, they train ~250 users and are involved in ~10 workshops and meetings.